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Publication Name World Journal of Methodology
Manuscript ID 117490
Country India
Received
2025-12-09 00:35
Peer-Review Started
2025-12-09 00:35
First Decision by Editorial Office Director
2026-01-20 09:17
Return for Revision
2026-01-20 09:17
Revised
2026-01-21 17:45
Publication Fee Transferred
Second Decision by Editor
2026-03-05 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-05 08:26
Articles in Press
2026-03-05 08:26
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-29 10:14
Publish the Manuscript Online
2026-07-10 10:11
ISSN 2222-0682 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Orthopedics
Manuscript Type Review
Article Title Fragility fracture risk prediction using quantitative magnetic resonance and Vertebral Bone Quality scoring beyond density
Manuscript Source Invited Manuscript
All Author List Sanjith Manian, Arunagiri Gunasekar, Naveen Jeyaraman, Arulkumar Nallakumarasamy, Sathish Muthu and Madhan Jeyaraman
ORCID
Author(s) ORCID Number
Naveen Jeyaraman http://orcid.org/0000-0002-4362-3326
Arulkumar Nallakumarasamy http://orcid.org/0000-0002-2445-2883
Sathish Muthu http://orcid.org/0000-0002-7143-4354
Madhan Jeyaraman http://orcid.org/0000-0002-9045-9493
Funding Agency and Grant Number
Corresponding Author Madhan Jeyaraman, MD, PhD, Researcher, Department of Orthopaedics, ACS Medical College and Hospital, Dr MGR Educational and Research Institute, Velappanchavadi, Chennai 600077, Tamil Nadu, India. madhanjeyaraman@gmail.com
Key Words Fragility fractures; Bone mineral density; Dual-energy X-ray absorptiometry; T2 mapping; Vertebral Bone Quality score
Core Tip Fragility fractures remain a global health challenge, with many occurring in patients without dual-energy X-ray absorptiometry-defined osteoporosis. Advanced imaging biomarkers such as quantitative magnetic resonance imaging (T1ρ, T2 mapping, proton density fat fraction, diffusion-weighted imaging) and Vertebral Bone Quality/modified Vertebral Bone Quality scoring provide deeper insights into bone microarchitecture and marrow composition. These tools enhance fracture risk prediction beyond bone mineral density, enabling radiation-free, opportunistic screening and artificial intelligence-driven models that bridge bone quantity and quality for improved prevention and management.
Publish Date 2026-07-10 10:11
Citation

Manian S, Gunasekar A, Jeyaraman N, Nallakumarasamy A, Muthu S, Jeyaraman M. Fragility fracture risk prediction using quantitative magnetic resonance and Vertebral Bone Quality scoring beyond density. World J Methodol 2026; 16(3): 117490

URL https://www.wjgnet.com/2222-0682/full/v16/i3/117490.htm
DOI https://doi.org/10.5662/wjm.v16.i3.117490
Full Article (PDF) WJM-16-117490-with-cover.pdf
Manuscript File 117490_Auto_Edited_094835.docx
Answering Reviewers 117490-answering-reviewers.pdf
Audio Core Tip 117490-audio.ogg
Conflict-of-Interest Disclosure Form 117490-conflict-of-interest-statement.pdf
Copyright License Agreement 117490-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 117490-non-native-speakers.pdf
Peer-review Report 117490-peer-reviews.pdf
Scientific Misconduct Check 117490-scientific-misconduct-check.png
Scientific Editor Work List 117490-scientific-editor-work-list.pdf
CrossCheck Report 117490-crosscheck-report.pdf