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5/29/2026 7:26:46 AM | Browse: 2 | Download: 15
Publication Name World Journal of Gastroenterology
Manuscript ID 117500
Country China
Received
2026-01-06 09:18
Peer-Review Started
2026-01-06 09:19
First Decision by Editorial Office Director
2026-01-19 08:52
Return for Revision
2026-01-19 08:52
Revised
2026-01-29 14:59
Publication Fee Transferred
2026-02-02 00:49
Second Decision by Editor
2026-03-17 03:07
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-17 10:07
Articles in Press
2026-03-17 10:07
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-15 01:47
Publish the Manuscript Online
2026-05-29 07:26
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Retrospective Study
Article Title Bone and renal safety of initial antiviral therapy using tenofovir alafenamide fumarate or entecavir for chronic hepatitis B
Manuscript Source Unsolicited Manuscript
All Author List Hui-Bin Ning, Hui-Ming Jin, Zhen Peng, Kuan Li and Jia Shang
ORCID
Author(s) ORCID Number
Hui-Bin Ning http://orcid.org/0000-0001-7117-5658
Kuan Li http://orcid.org/0000-0002-9778-7350
Jia Shang http://orcid.org/0000-0001-9197-8773
Funding Agency and Grant Number
Corresponding Author Jia Shang, Chief Physician, Department of Infectious Diseases, Henan Provincial People's Hospital, No. 7 Weiwu Road, Jinshui District, Zhengzhou 450000, Henan Province, China. shangjia666@126.com
Key Words Chronic hepatitis B; Entecavir; Tenofovir alafenamide fumarate; Bone safety; Renal safety
Core Tip Nucleoside/nucleotide analogs are currently the core drugs for the antiviral treatment of chronic hepatitis B (CHB). Among them, entecavir and tenofovir alafenamide fumarate (TAF) are recommended as first-line treatment regimens in domestic and international guidelines due to their potent antiviral activity and low resistance rates. However, direct comparative data between TAF and entecavir remain limited, particularly in long-term follow-up studies of Chinese CHB populations. The long-term differences in bone and renal safety between TAF and entecavir warrant further investigation. Therefore, this study aims to provide critical insights for optimizing individualized treatment strategies for CHB by comparing the clinical efficacy and safety profiles of entecavir and TAF.
Publish Date 2026-05-29 07:26
Citation

Ning HB, Jin HM, Peng Z, Li K, Shang J. Bone and renal safety of initial antiviral therapy using tenofovir alafenamide fumarate or entecavir for chronic hepatitis B. World J Gastroenterol 2026; 32(22): 117500

URL https://www.wjgnet.com/1007-9327/full/v32/i22/117500.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i22.117500
Full Article (PDF) WJG-32-117500-with-cover.pdf
Manuscript File 117500_Auto_Edited_110859.docx
Answering Reviewers 117500-answering-reviewers.pdf
Audio Core Tip 117500-audio.mp3
Biostatistics Review Certificate 117500-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 117500-conflict-of-interest-statement.pdf
Copyright License Agreement 117500-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 117500-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 117500-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 117500-non-native-speakers.pdf
Peer-review Report 117500-peer-reviews.pdf
Scientific Misconduct Check 117500-scientific-misconduct-check.png
Scientific Editor Work List 117500-scientific-editor-work-list.pdf
CrossCheck Report 117500-crosscheck-report.pdf