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Publication Name World Journal of Gastroenterology
Manuscript ID 117508
Country China
Received
2025-12-09 03:59
Peer-Review Started
2025-12-09 03:59
First Decision by Editorial Office Director
2025-12-24 10:42
Return for Revision
2025-12-24 10:42
Revised
2026-01-06 12:59
Publication Fee Transferred
Second Decision by Editor
2026-02-03 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-03 05:28
Articles in Press
2026-02-03 05:28
Edit the Manuscript by Language Editor
2026-02-10 22:10
Typeset the Manuscript
2026-06-15 01:42
Publish the Manuscript Online
2026-06-30 13:40
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Correspondence
Article Title Origin recognition complex subunit 1 as a biomarker in hepatitis B virus-related hepatocellular carcinoma: Promises and pitfalls
Manuscript Source Unsolicited Manuscript
All Author List Lian-Bang Wang, Xi-Ming Wang, Xin-Ya Zhao and Gong-Zheng Wang
ORCID
Author(s) ORCID Number
Xin-Ya Zhao http://orcid.org/0000-0001-5856-347X
Gong-Zheng Wang http://orcid.org/0000-0002-7681-9368
Funding Agency and Grant Number
Corresponding Author Gong-Zheng Wang, MD, PhD, Department of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No. 324 Jingwu Road, Jinan 250021, Shandong Province, China. wanggz0322@163.com
Key Words Hepatocellular carcinoma; Hepatitis B virus; Origin recognition complex subunit 1; Diagnostic biomarker; Alpha-fetoprotein-negative
Core Tip Serum origin recognition complex subunit 1 has emerged as a potential biomarker for hepatitis B virus-related hepatocellular carcinoma, which improved diagnostic accuracy when combined with extra spindle pole bodies-like 1 and alpha-fetoprotein. These indicators may eventually be integrated into a unified surveillance model to enhance early detection. Large, multicenter prospective studies and standardized assay development are essential to confirm its applicability across diverse clinical settings.
Publish Date 2026-06-30 13:40
Citation

Wang LB, Wang XM, Zhao XY, Wang GZ. Origin recognition complex subunit 1 as a biomarker in hepatitis B virus-related hepatocellular carcinoma: Promises and pitfalls. World J Gastroenterol 2026; 32(26): 117508

URL https://www.wjgnet.com/1007-9327/full/v32/i26/117508.htm
DOI https://doi.org/10.3748/wjg.117508
Full Article (PDF) WJG-32-117508-with-cover.pdf
Manuscript File 117508_Auto_Edited_084015.docx
Answering Reviewers 117508-answering-reviewers.pdf
Audio Core Tip 117508-audio.wav
Conflict-of-Interest Disclosure Form 117508-conflict-of-interest-statement.pdf
Copyright License Agreement 117508-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 117508-non-native-speakers.pdf
Peer-review Report 117508-peer-reviews.pdf
Scientific Misconduct Check 117508-scientific-misconduct-check.png
Scientific Editor Work List 117508-scientific-editor-work-list.pdf
CrossCheck Report 117508-crosscheck-report.pdf