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5/27/2026 1:21:58 PM | Browse: 6 | Download: 0
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 117633
Country China
Received
2025-12-18 11:14
Peer-Review Started
2025-12-18 11:14
First Decision by Editorial Office Director
2026-01-14 01:57
Return for Revision
2026-01-14 01:57
Revised
2026-01-21 03:05
Publication Fee Transferred
2026-01-22 15:36
Second Decision by Editor
2026-03-04 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-04 06:56
Articles in Press
2026-03-04 06:56
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-12 01:11
Publish the Manuscript Online
2026-05-27 13:21
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Massive gastric perforation in a patient with mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes: A case report
Manuscript Source Unsolicited Manuscript
All Author List Zhen-Xing Zhang, Bo-Wen Jin, Shan Wang and Ke-Long Tao
ORCID
Author(s) ORCID Number
Zhen-Xing Zhang http://orcid.org/0000-0002-0334-172X
Shan Wang http://orcid.org/0000-0001-8291-1024
Ke-Long Tao http://orcid.org/0000-0001-8080-1200
Funding Agency and Grant Number
Funding Agency Grant Number
Shaoxing Bureau of Science and Technology Foundation, Zhejiang Province, China No.2023A14006
Corresponding Author Ke-Long Tao, Professor, Department of Gastrointestinal Surgery, Shaoxing People’s Hospital (The First Affiliated Hospital of Shaoxing University), No. 568 Zhongxing North Road, Shaoxing 312000, Zhejiang Province, China. fykelong@163.com
Key Words Mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes; Gastrointestinal perforation; Gastric perforation; Massive gastric perforation; Case report
Core Tip Massive gastric perforation is an exceptionally rare but life-threatening gastrointestinal complication of mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS). MELAS concurrent with gastrointestinal perforation is rare, and concurrent with massive gastric perforation is extremely rare. This case highlights that acute abdominal pain in MELAS patients may signal catastrophic perforation requiring urgent imaging and surgical intervention. Early recognition and multidisciplinary management are essential to reduce morbidity and improve outcomes.
Publish Date 2026-05-27 13:21
Citation

Zhang ZX, Jin BW, Wang S, Tao KL. Massive gastric perforation in a patient with mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes: A case report. World J Gastrointest Surg 2026; 18(5): 117633

URL https://www.wjgnet.com/1948-9366/full/v18/i5/117633.htm
DOI https://dx.doi.org/10.4240/wjgs.v18.i5.117633
Full Article (PDF) WJGS-18-117633-with-cover.pdf
CARE Checklist–2016 117633-CARE-Checklist-2016.pdf
Manuscript File 117633_Auto_Edited_100932.docx
Answering Reviewers 117633-answering-reviewers.pdf
Audio Core Tip 117633-audio.mp3
Conflict-of-Interest Disclosure Form 117633-conflict-of-interest-statement.pdf
Copyright License Agreement 117633-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 117633-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 117633-non-native-speakers.pdf
Peer-review Report 117633-peer-reviews.pdf
Scientific Misconduct Check 117633-scientific-misconduct-check.png
Scientific Editor Work List 117633-scientific-editor-work-list.pdf
CrossCheck Report 117633-crosscheck-report.pdf