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3/27/2026 12:17:00 PM | Browse: 1 | Download: 0
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 117693
Country China
Received
2025-12-26 10:02
Peer-Review Started
2025-12-26 10:03
First Decision by Editorial Office Director
2026-01-09 07:38
Return for Revision
2026-01-09 07:38
Revised
2026-01-19 17:15
Publication Fee Transferred
2026-01-20 03:29
Second Decision by Editor
2026-02-03 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-03 07:59
Articles in Press
2026-02-03 07:59
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-18 06:49
Publish the Manuscript Online
2026-03-27 12:17
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Randomized Controlled Trial
Article Title Crohn’s disease-related perianal fistula: A clinic research
Manuscript Source Unsolicited Manuscript
All Author List Wei-Feng Zhang, Wen-Ting Fan, Wei-Wei Gao, Zheng Wu, Ran-Ran Liu and Cheng-Wei Ruan
ORCID
Author(s) ORCID Number
Wei-Feng Zhang http://orcid.org/0000-0003-3594-6480
Wen-Ting Fan http://orcid.org/0009-0000-8258-5003
Wei-Wei Gao http://orcid.org/0009-0004-5865-0732
Zheng Wu http://orcid.org/0009-0006-7366-3157
Ran-Ran Liu http://orcid.org/0009-0004-4793-9573
Cheng-Wei Ruan http://orcid.org/0000-0003-3893-6763
Funding Agency and Grant Number
Funding Agency Grant Number
Construction Project of High Level Hospital of Jiangsu Province GSPJS202508
Corresponding Author Cheng-Wei Ruan, Researcher, Department of Colorectal Surgery, The Affiliated Hospital of Xuzhou Medical University, No. 99 Huaihai West Road, Xuzhou 221004, Jiangsu Province, China. ruancw666@126.com
Key Words Loose seton; Mahuang Shengma Decoction; Crohn’s disease-related perianal fistula; External application; Clinical study
Core Tip This study is the first to evaluate the efficacy of the comprehensive regimen of seton drainage combined with oral and external Traditional Chinese medicine (TCM) for the treatment of simple Crohn’s disease-related perianal fistula. The results demonstrate that this regimen can significantly shorten wound healing time, improve TCM syndromes and perianal symptoms, and has a favorable safety profile, thereby providing a novel integrated TCM and Western medicine therapeutic strategy for clinical practice.
Publish Date 2026-03-27 12:17
Citation

Zhang WF, Fan WT, Gao WW, Wu Z, Liu RR, Ruan CW. Crohn’s disease-related perianal fistula: A clinic research. World J Gastrointest Surg 2026; 18(3): 117693

URL https://www.wjgnet.com/1948-9366/full/v18/i3/117693.htm
DOI https://dx.doi.org/10.4240/wjgs.v18.i3.117693
Full Article (PDF) WJGS-18-117693-with-cover.pdf
CONSORT 2010 Statement 117693-CONSORT-2010-statement.pdf
Manuscript File 117693_Auto_Edited_005509.docx
Answering Reviewers 117693-answering-reviewers.pdf
Audio Core Tip 117693-audio.m4a
Biostatistics Review Certificate 117693-biostatistics-statement.pdf
Clinical Trial Registration Statement 117693-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 117693-conflict-of-interest-statement.pdf
Copyright License Agreement 117693-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 117693-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 117693-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 117693-non-native-speakers.pdf
Peer-review Report 117693-peer-reviews.pdf
Scientific Misconduct Check 117693-scientific-misconduct-check.png
Scientific Editor Work List 117693-scientific-editor-work-list.pdf
CrossCheck Report 117693-crosscheck-report.pdf