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Publication Name World Journal of Stem Cells
Manuscript ID 117707
Country South Korea
Received
2025-12-15 03:48
Peer-Review Started
2025-12-15 03:48
First Decision by Editorial Office Director
2026-01-09 07:58
Return for Revision
2026-01-09 07:58
Revised
2026-01-17 10:17
Publication Fee Transferred
2026-01-19 01:59
Second Decision by Editor
2026-03-02 02:51
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-09 09:09
Articles in Press
2026-03-09 09:09
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-31 00:50
Publish the Manuscript Online
2026-04-20 08:05
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Basic Study
Article Title Hypoxia-conditioned extracellular vesicles from human amniotic membrane stem cells attenuate D-galactose-induced aging in mice
Manuscript Source Invited Manuscript
All Author List Khan-Erdene Tsolmon, Zolzaya Bavuu, Solar Sora Kim, Heon-Sang Jeong, Dongsun Park and Yun-Bae Kim
ORCID
Author(s) ORCID Number
Khan-Erdene Tsolmon http://orcid.org/0009-0007-3572-5772
Zolzaya Bavuu http://orcid.org/0009-0004-4055-2042
Solar Sora Kim http://orcid.org/0009-0005-2246-090X
Heon-Sang Jeong http://orcid.org/0000-0003-0349-4483
Dongsun Park http://orcid.org/0000-0001-6042-5949
Yun-Bae Kim http://orcid.org/0000-0003-1340-041X
Funding Agency and Grant Number
Funding Agency Grant Number
Regional Innovation System & Education Global University 30 Program Through the Chungbuk Regional Innovation System & Education Center 2025-RISE-11-014
Corresponding Author Yun-Bae Kim, PhD, Professor, College of Veterinary Medicine, Chungbuk National University, 1 Chungdaero (Gaesin-dong), Cheongju 28644, Chungbuk, South Korea. solar93@cbu.ac.kr
Key Words Aging; Physical activity; Cognitive function; Amniotic membrane stem cell; Extracellular vesicle; Growth factor; Neurotrophic factor
Core Tip We obtained a large amount of extracellular vesicles containing high concentrations of growth factors and neurotrophic factors via hypoxic cultivation of amniotic membrane stem cells. The extracellular vesicles ameliorated physical and cognitive dysfunctions by recovering anti-aging factors and energy sources, in the brain and muscles, such as brain-derived neurotrophic factor, sirtuin 1, glycogen, acetylcholine, and antioxidation.
Publish Date 2026-04-20 08:05
Citation

Tsolmon KE, Bavuu Z, Kim SS, Jeong HS, Park D, Kim YB. Hypoxia-conditioned extracellular vesicles from human amniotic membrane stem cells attenuate D-galactose-induced aging in mice. World J Stem Cells 2026; 18(4): 117707

URL https://www.wjgnet.com/1948-0210/full/v18/i4/117707.htm
DOI https://dx.doi.org/10.4252/wjsc.v18.i4.117707
Full Article (PDF) WJSC-18-117707-with-cover.pdf
The ARRIVE Guidelines 117707-The-ARRIVE-Guidelines.pdf
Manuscript File 117707_Auto_Edited_082334.docx
Answering Reviewers 117707-answering-reviewers.pdf
Audio Core Tip 117707-audio.m4a
Biostatistics Review Certificate 117707-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 117707-conflict-of-interest-statement.pdf
Copyright License Agreement 117707-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 117707-institutional-animal-care-and-use-committee-statement.pdf
Institutional Review Board Approval Form or Document 117707-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 117707-non-native-speakers.pdf
Peer-review Report 117707-peer-reviews.pdf
Scientific Misconduct Check 117707-scientific-misconduct-check.png
Scientific Editor Work List 117707-scientific-editor-work-list.pdf
CrossCheck Report 117707-crosscheck-report.pdf