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1/27/2015 3:33:00 PM | Browse: 1317 | Download: 932
Publication Name World Journal of Gastroenterology
Manuscript ID 11772
Country/Territory Japan
Received
2014-06-03 09:33
Peer-Review Started
2014-06-03 21:05
To Make the First Decision
2014-07-21 14:17
Return for Revision
2014-07-28 16:12
Revised
2014-07-30 16:15
Second Decision
2014-09-19 09:07
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-09-19 09:54
Articles in Press
2014-09-19 10:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-10-20 18:29
Typeset the Manuscript
2015-01-18 16:02
Publish the Manuscript Online
2015-01-27 15:33
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Prospective Study
Article Title Impact of discontinuing non-steroidal antiinflammatory drugs on long-term recurrence in colonic diverticular bleeding
Manuscript Source Unsolicited Manuscript
All Author List Naoyoshi Nagata, Ryota Niikura, Tomonori Aoki, Takuro Shimbo, Katsunori Sekine, Hidetaka Okubo, Kazuhiro Watanabe, Toshiyuki Sakurai, Chizu Yokoi, Junichi Akiyama, Mikio Yanase, Masashi Mizokami and Naomi Uemura
Funding Agency and Grant Number
Funding Agency Grant Number
Research from the National Center for Global Health and Medicine 26A-201
Corresponding Author Naoyoshi Nagata, MD, Department of Gastroenterology and Hepatology, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku, Tokyo 162-8655, Japan. nnagata_ncgm@yahoo.co.jp
Key Words Non-steroidal anti-inflammatories; Drug withdrawal; Diverticular hemorrhage; Hemodialysis; Antithrombotic drugs
Core Tip The probability of recurrence of diverticular bleeding at 1, 12, and 24 mo was 3.1%, 27%, and 38%, respectively. Of the 41 non-steroidal anti-inflammatory drugs (NSAIDs) users on admission, 26 (63%) discontinued NSAID use at discharge. The probability of recurrence at 12 mo was 9.4% in discontinuing NSAID users compared with 77% in continuing users (P < 0.01, log-rank test). The hazard ratio for recurrence in the discontinuing NSAIDs users was 0.06 after adjusting for age > 70 years, right-sided diverticula, history of hypertension, and hemodialysis. No patients developed cerebrocardiovascular events during follow-up. This study provides new information on risk reduction strategies for diverticular bleeding.
Publish Date 2015-01-27 15:33
Citation Nagata N, Niikura R, Aoki T, Shimbo T, Sekine K, Okubo H, Watanabe K, Sakurai T, Yokoi C, Akiyama J, Yanase M, Mizokami M, Uemura N. Impact of discontinuing non-steroidal antiinflammatory drugs on long-term recurrence in colonic diverticular bleeding. World J Gastroenterol 2015; 21(4): 1292-1298
URL http://www.wjgnet.com/1007-9327/full/v21/i4/1292.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i4.1292
Full Article (PDF) WJG-21-1292.pdf
Full Article (Word) WJG-21-1292.doc
Manuscript File 11772-Review.doc
Answering Reviewers 11772-Answering reviewers.pdf
Copyright License Agreement 11772-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 11772-Language certificate.pdf
Peer-review Report 11772-Peer review.pdf
Scientific Misconduct Check 11772-CorssCheck.jpg
Scientific Editor Work List 11772-Scientific editor work list.pdf