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Publication Name World Journal of Diabetes
Manuscript ID 117759
Country China
Received
2025-12-15 05:39
Peer-Review Started
2025-12-15 09:51
First Decision by Editorial Office Director
2026-01-09 10:08
Return for Revision
2026-01-09 10:08
Revised
2026-01-15 09:11
Publication Fee Transferred
Second Decision by Editor
2026-01-26 02:51
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-26 07:10
Articles in Press
2026-01-26 07:10
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-06-03 15:39
Publish the Manuscript Online
2026-06-11 11:24
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Correspondence
Article Title Hepatic transcriptome and metabolome analysis of Jiangtang Tiaozhi formula
Manuscript Source Invited Manuscript
All Author List Shu-Meng Huang and Di-Guang Wen
ORCID
Author(s) ORCID Number
Di-Guang Wen http://orcid.org/0009-0008-8359-0793
Funding Agency and Grant Number
Corresponding Author Di-Guang Wen, Academic Fellow, PhD, Professor, Department of Endocrinology, Yuyao People's Hospital, <institution>Second Affiliated Hospital of Chongqing Medical University</institution>, <addr-line>Chongqing</addr-line>, <country>People’s Republic of China</country>, Yuyao 315400, Zhejiang Province, China. 2018110626@stu.cqmu.edu.cn
Key Words Glycolipid metabolic disorder; Jiangtang Tiaozhi formula; Hepatic transcriptome; Hepatic metabolome; Multi-omics analysis; Insulin resistance; Lipid metabolism; Glucose metabolism
Core Tip This commentary discusses a recent hepatic transcriptomic and metabolomic study that elucidates the regulatory effects of Jiangtang Tiaozhi formula on glycolipid metabolism. We emphasize key strengths of the multi-omics strategy and highlight critical issues that warrant further investigation, including dose-response relationships, cellular resolution, mechanistic causality, active constituent identification, and long-term safety evaluation. By integrating systems biology and translational perspectives, this work underscores the potential of traditional Chinese medicine-based therapies to advance precision medicine approaches for metabolic disorders.
Publish Date 2026-06-11 11:24
Citation

Huang SM, Wen DG. Hepatic transcriptome and metabolome analysis of Jiangtang Tiaozhi formula. World J Diabetes 2026; 17(6): 117759

URL https://www.wjgnet.com/1948-9358/full/v17/i6/117759.htm
DOI https://doi.org/10.4239/wjd.117759
Full Article (PDF) WJD-17-117759-with-cover.pdf
Manuscript File 117759_Auto_Edited_085436.docx
Answering Reviewers 117759-answering-reviewers.pdf
Audio Core Tip 117759-audio.mp3
Conflict-of-Interest Disclosure Form 117759-conflict-of-interest-statement.pdf
Copyright License Agreement 117759-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 117759-non-native-speakers.pdf
Peer-review Report 117759-peer-reviews.pdf
Scientific Misconduct Check 117759-scientific-misconduct-check.png
Scientific Editor Work List 117759-scientific-editor-work-list.pdf
CrossCheck Report 117759-crosscheck-report.pdf