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Publication Name World Journal of Gastroenterology
Manuscript ID 117778
Country Italy
Received
2025-12-24 07:03
Peer-Review Started
2025-12-24 07:03
First Decision by Editorial Office Director
2026-01-30 09:07
Return for Revision
2026-01-30 09:07
Revised
2026-02-12 18:11
Publication Fee Transferred
2026-03-05 13:13
Second Decision by Editor
2026-04-21 02:49
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-04-21 08:04
Articles in Press
2026-04-21 08:04
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-06-28 10:13
Publish the Manuscript Online
2026-07-23 06:25
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Randomized Controlled Trial
Article Title When and where: A study on gastric cancer recurrence after neoadjuvant/perioperative chemotherapy
Manuscript Source Unsolicited Manuscript
All Author List Manlio Monti, Bianca Ceredi, Flavia Foca, Paolo Morgagni, Massimo Framarini, Bernadette Vertogen, Daniele Marrelli, Franco Roviello, Uberto Fumagalli Romario, Silvia Bozzarelli, Annibale Donini, Luigina Graziosi, Federica Filippini, Maria Bencivenga, Carlo Milandri, Gianni Mura, Gian Luca Baiocchi, Stefano Rausei, Chiara Molinari and Alessandro Passardi
ORCID
Author(s) ORCID Number
Manlio Monti http://orcid.org/0000-0003-2982-1382
Flavia Foca http://orcid.org/0000-0002-5529-4769
Paolo Morgagni http://orcid.org/0000-0002-1564-2415
Massimo Framarini http://orcid.org/0000-0002-7374-8998
Daniele Marrelli http://orcid.org/0000-0003-2066-1618
Uberto Fumagalli Romario http://orcid.org/0000-0001-5163-4546
Silvia Bozzarelli http://orcid.org/0000-0002-8118-7342
Annibale Donini http://orcid.org/0000-0002-8846-7208
Luigina Graziosi http://orcid.org/0000-0003-4929-0515
Carlo Milandri http://orcid.org/0000-0001-6932-8977
Gian Luca Baiocchi http://orcid.org/0000-0003-2402-2178
Stefano Rausei http://orcid.org/0000-0002-6676-2935
Chiara Molinari http://orcid.org/0000-0003-1011-5656
Alessandro Passardi http://orcid.org/0000-0002-7099-240X
Funding Agency and Grant Number
Corresponding Author Flavia Foca, Researcher, Unit of Biostatistics and Clinical Trials, IRCCS Istituto Scientifico Romagnolo per lo Studio dei Tumori (IRST) “Dino Amadori”, Via P. Maroncelli 40, Meldola 47014, Emilia-Romagna, Italy. flavia.foca@irst.emr.it
Key Words Gastric cancer; Neoadjuvant chemotherapy; Perioperative chemotherapy; Time of recurrence; Site of recurrence; Postoperative recurrence
Core Tip This randomized study provides long-term data on recurrence patterns after neoadjuvant or perioperative chemotherapy for resectable gastric cancer. Most relapses occurred at distant sites, with the highest risk within the first two years after surgery. These findings support risk stratification particularly given by interaction between tumor regression score and lymph nodes involvement. Time-dependent modelling suggested that the intestinal subtype is associated with a decreasing recurrence risk over time; however, this finding requires further validation.
Publish Date 2026-07-23 06:25
Citation

Monti M, Ceredi B, Foca F, Morgagni P, Framarini M, Vertogen B, Marrelli D, Roviello F, Fumagalli Romario U, Bozzarelli S, Donini A, Graziosi L, Filippini F, Bencivenga M, Milandri C, Mura G, Baiocchi GL, Rausei S, Molinari C, Passardi A. When and where: A study on gastric cancer recurrence after neoadjuvant/perioperative chemotherapy. World J Gastroenterol 2026; 32(30): 117778
URL https://www.wjgnet.com/1007-9327/full/v32/i30/117778.htm
DOI https://doi.org/10.3748/wjg.117778
Full Article (PDF) WJG-32-117778-with-cover.pdf
CONSORT 2010 Statement 117778-CONSORT-2010-statement.pdf
Manuscript File 117778_Auto_Edited_084234.docx
Answering Reviewers 117778-answering-reviewers.pdf
Audio Core Tip 117778-audio.opus
Biostatistics Review Certificate 117778-biostatistics-statement.pdf
Clinical Trial Registration Statement 117778-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 117778-conflict-of-interest-statement.pdf
Copyright License Agreement 117778-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 117778-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 117778-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 117778-non-native-speakers.pdf
Peer-review Report 117778-peer-reviews.pdf
Scientific Misconduct Check 117778-scientific-misconduct-check.png
Scientific Editor Work List 117778-scientific-editor-work-list.pdf
CrossCheck Report 117778-crosscheck-report.pdf
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