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Articles Published Processes
6/30/2026 11:45:07 AM | Browse: 3 | Download: 15
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Received |
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2025-12-23 10:00 |
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Peer-Review Started |
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2025-12-23 10:00 |
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First Decision by Editorial Office Director |
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2026-02-09 09:18 |
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Return for Revision |
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2026-02-09 09:18 |
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Revised |
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2026-02-23 09:16 |
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Publication Fee Transferred |
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2026-02-28 10:01 |
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Second Decision by Editor |
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2026-04-02 02:37 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-04-02 06:16 |
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Articles in Press |
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2026-04-02 06:16 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-05-29 10:09 |
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Publish the Manuscript Online |
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2026-06-30 11:45 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Observational Study |
| Article Title |
Tardive dyskinesia-depression association in Chinese patients with chronic schizophrenia: The mediating role of insomnia and gender differences
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
San-Rong Xiao, Qiu-Yue Yin, Jing-Min Zhu, Yan Liu, Wen-Zhi Tan, Ting Wang and Xiang-Yang Zhang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Xiang-Yang Zhang, Associate Research Scientist, PhD, Postdoc, Professor, Research Fellow, Institute of Psychology, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing,China., No. 16 Lincui Road, Chaoyang District, Beijing 100101, China. zhangxy@psych.ac.cn |
| Key Words |
Tardive dyskinesia; Depression; Chronic schizophrenia; Insomnia; Mediation effect; Gender differences |
| Core Tip |
This study of 669 Chinese patients with chronic schizophrenia demonstrates that tardive dyskinesia (TD) is associated with increased depressive severity, with insomnia partially mediating this relationship (accounting for 38% of the total effect). Gender differences were identified: Female patients with TD exhibited more severe overall depression, greater diurnal variation, and increased psychomotor retardation, whereas male patients with TD differed from non-TD males only in diurnal variation. These findings point to the critical need for systematic evaluation of insomnia and depression in the TD patient population and highlight the need for gender-specific interventions to optimize care in this vulnerable population. |
| Publish Date |
2026-06-30 11:45 |
| Citation |
Xiao SR, Yin QY, Zhu JM, Liu Y, Tan WZ, Wang T, Zhang XY. Tardive dyskinesia-depression association in Chinese patients with chronic schizophrenia: The mediating role of insomnia and gender differences. World J Psychiatry 2026; 16(7): 117824
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| URL |
https://www.wjgnet.com/2220-3206/full/v16/i7/117824.htm |
| DOI |
https://doi.org/10.5498/wjp.117824 |
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