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Articles Published Processes
5/26/2026 5:34:20 AM | Browse: 1 | Download: 0
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Received |
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2025-12-23 06:53 |
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Peer-Review Started |
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2025-12-23 06:53 |
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First Decision by Editorial Office Director |
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2026-02-03 10:20 |
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Return for Revision |
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2026-02-03 10:20 |
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Revised |
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2026-02-16 13:41 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-03-09 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-09 09:04 |
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Articles in Press |
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2026-03-09 09:04 |
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Edit the Manuscript by Language Editor |
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2026-03-13 15:21 |
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Typeset the Manuscript |
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2026-05-19 02:03 |
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Publish the Manuscript Online |
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2026-05-26 05:34 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Methods improving endoscopic retrograde cholangiopancreatography brush cytology in malignant biliary strictures
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Kleoniki Kordeni, Antonios Vezakis, Theodoros Voulgaris, Athina Sotirianakou, Ekaterini Politi and Maria Gazouli |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Maria Gazouli, Department of Basic Medical Sciences, Medical School, National and Kapodistrian University of Athens, No. 176 Michalakopoulou, Athens 11527, Greece. mgazouli@med.uoa.gr |
| Key Words |
Biliary stricture; Pancreatic cancer; Cholangiocarcinoma; Next generation sequence; Fluorescence in situ hybridization; Endoscopic retrograde cholangiopancreatography; Brushing; MicroRNA |
| Core Tip |
Endoscopic retrograde cholangiopancreatography brush cytology remains a first-line sampling technique for indeterminate biliary strictures but suffers from limited sensitivity despite high specificity. Technical refinements including increased brushing passes, rapid on-site cytopathology evaluation, sheath-rinse techniques, and combined bile aspiration or fluoroscopic-guided biopsy improve cellular yield and diagnostic accuracy. Integration of advanced molecular diagnostics such as fluorescence in situ hybridization, next-generation sequencing, and microRNA profiling further enhances detection rates and enables identification of actionable genomic alterations. A multimodal diagnostic strategy combining optimized sampling techniques with molecular analysis represents the most effective current approach for improving early diagnosis and clinical decision-making in malignant biliary strictures. |
| Publish Date |
2026-05-26 05:34 |
| Citation |
Kordeni K, Vezakis A, Voulgaris T, Sotirianakou A, Politi E, Gazouli M. Methods improving endoscopic retrograde cholangiopancreatography brush cytology in malignant biliary strictures. World J Gastroenterol 2026; 32(21): 117828 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i21/117828.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i21.117828 |
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