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Articles Published Processes
7/10/2026 10:11:17 AM | Browse: 0 | Download: 0
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Received |
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2025-12-18 10:46 |
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Peer-Review Started |
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2025-12-18 10:46 |
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First Decision by Editorial Office Director |
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2026-01-07 02:57 |
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Return for Revision |
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2026-01-07 02:57 |
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Revised |
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2026-01-17 17:22 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-03-02 02:37 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-02 10:11 |
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Articles in Press |
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2026-03-02 10:11 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-06-09 03:59 |
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Publish the Manuscript Online |
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2026-07-10 10:11 |
| ISSN |
2222-0682 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Functional dyspepsia and risk of Barrett’s esophagus and dysplasia: A propensity-matched multicenter retrospective cohort study
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Muhammad Hassaan Arif Maan, Soban Maan, Muhammad Waleed, Muhammad Mursaleen Ahmad, Ritik Mahaveer Goyal, Amir Humza Sohail, Yazan Abboud, Sunnia Khan, Swapna Gayam and Justin Kupec |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Muhammad Hassaan Arif Maan, MD, Department of Medicine, Rutgers New Jersey Medical School, Stadium Road, Newark, NJ 07103, United States. m.hassaanmaan@gmail.com |
| Key Words |
Functional dyspepsia; Barrett’s esophagus; Gastroesophageal reflux disease; Esophageal adenocarcinoma; Dysplasia; Risk stratification; Propensity score matching; Diagnostic overlap; Acid reflux |
| Core Tip |
This large-scale cohort study of over 3.6 million patients demonstrates that individuals diagnosed with functional dyspepsia (FD) have a substantially elevated risk for Barrett's esophagus and dysplasia compared to matched controls. Interestingly, this increased risk persisted even after adjusting for documented gastroesophageal reflux disease (GERD). Whether this reflects true pathophysiologic overlap, diagnostic misclassification (especially considering overlap in presentation for FD and gastroesophageal reflux disease), or shared predisposing factors, patients diagnosed with FD represent a higher-risk population warranting reconsideration of current diagnostic strategies, including objective reflux testing and risk-stratified endoscopic evaluation. |
| Publish Date |
2026-07-10 10:11 |
| Citation |
Maan MHA, Maan S, Waleed M, Ahmad MM, Goyal RM, Sohail AH, Abboud Y, Khan S, Gayam S, Kupec J. Functional dyspepsia and risk of Barrett’s esophagus and dysplasia: A propensity-matched multicenter retrospective cohort study. World J Methodol 2026; 16(3): 117891
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| URL |
https://www.wjgnet.com/2222-0682/full/v16/i3/117891.htm |
| DOI |
https://doi.org/10.5662/wjm.117891 |
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