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Articles Published Processes
6/9/2026 9:23:55 AM | Browse: 0 | Download: 0
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Received |
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2026-01-16 06:25 |
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Peer-Review Started |
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2026-01-16 06:29 |
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First Decision by Editorial Office Director |
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2026-02-03 08:20 |
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Return for Revision |
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2026-02-03 08:20 |
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Revised |
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2026-02-13 00:33 |
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Publication Fee Transferred |
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2026-02-18 14:54 |
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Second Decision by Editor |
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2026-03-11 02:37 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-11 09:42 |
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Articles in Press |
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2026-03-11 09:42 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-04-24 05:33 |
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Publish the Manuscript Online |
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2026-06-09 09:23 |
| ISSN |
1948-5204 (online) |
| Open Access |
Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Gamma delta T-cell infusion plus chemotherapy induces long-term remission of gastric cancer after immunochemotherapy failure: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yi-Hua Wu, Li-Yuan Bai, Horng-Ren Yang, Kai-Po Chang and Long-Bin Jeng |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Long-Bin Jeng, Chief, Professor, Cell Therapy Center, China Medical University Hospital, No. 2 Yude Road, North District, Taichung 404327, Taiwan. 010919@tool.caaumed.org.tw |
| Key Words |
Gamma delta T-cell; Immune checkpoint therapy; Chemotherapy; Trifluridine/tipiracil; Ramucirumab; Antigen presentation; Prognosis; Metastatic; Advanced gastric cancer; Case report |
| Core Tip |
Long-term survival after progression on immunochemotherapy is uncommon in metastatic gastric cancer. We report a patient with stage IV gastric adenocarcinoma who achieved radiologic and pathologic complete response after the addition of autologous gamma delta (γδ) T-cell infusions to ramucirumab and trifluridine/tipiracil. Because γδ T cells recognize stressed tumor cells independent of the major histocompatibility complex, they may retain antitumor activity even when immune checkpoint blockade fails. This case is hypothesis-generating and supports further investigation of γδ T-cell-based immunotherapy in gastric cancer. |
| Publish Date |
2026-06-09 09:23 |
| Citation |
Wu YH, Bai LY, Yang HR, Chang KP, Jeng LB. Gamma delta T-cell infusion plus chemotherapy induces long-term remission of gastric cancer after immunochemotherapy failure: A case report. World J Gastrointest Oncol 2026; 18(6): 117904
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| URL |
https://www.wjgnet.com/1948-5204/full/v18/i6/117904.htm |
| DOI |
https://doi.org/10.4251/wjgo.v18.i6.117904 |
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