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Articles Published Processes
4/21/2026 8:57:47 AM | Browse: 29 | Download: 93
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Received |
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2025-12-22 07:54 |
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Peer-Review Started |
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2025-12-22 07:54 |
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First Decision by Editorial Office Director |
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2026-01-16 06:48 |
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Return for Revision |
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2026-01-16 06:48 |
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Revised |
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2026-01-27 14:38 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-03-23 02:49 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-23 06:26 |
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Articles in Press |
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2026-03-23 06:26 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-04-10 06:23 |
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Publish the Manuscript Online |
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2026-04-21 08:57 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Glucocorticoid therapy in acute liver failure: Survival outcomes, predictors, and a response prediction model
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yu-Lan He, Xue-Hong Yin, Xiao-Tong Xu, Juan Li and Qing-Hua Meng |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Qing-Hua Meng, Professor, Hepatic Disease and Oncology Minimally lnvasive Interventional Center, Beijing YouAn Hospital, Capital Medical University, No. 8 Xitoutiao, Youanmen Wai, Fengtai District, Beijing 100069, China. meng_qh0805@ccmu.edu.cn |
| Key Words |
Acute liver failure; Glucocorticoids; Prediction model; Survival; Efficacy |
| Core Tip |
This retrospective cohort study of 179 acute liver failure patients demonstrates that glucocorticoid (GC) therapy significantly improves 28-day survival (58.3% vs 30.5%, P < 0.001). An early increase in prothrombin activity ≥ 4.5% by day 3, alongside baseline model for end-stage liver disease score < 28.5 and blood ammonia < 135.5 μg/dL, forms a highly accurate predictive model for GC response (95.2% accuracy). This model provides a practical tool to select patients most likely to benefit from GC treatment. |
| Publish Date |
2026-04-21 08:57 |
| Citation |
He YL, Yin XH, Xu XT, Li J, Meng QH. Glucocorticoid therapy in acute liver failure: Survival outcomes, predictors, and a response prediction model. World J Hepatol 2026; 18(4): 117905 |
| URL |
https://www.wjgnet.com/1948-5182/full/v18/i4/117905.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v18.i4.117905 |
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