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5/26/2026 5:34:18 AM | Browse: 3 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 117959
Country Sweden
Received
2025-12-22 07:08
Peer-Review Started
2025-12-22 07:08
First Decision by Editorial Office Director
2026-01-16 07:26
Return for Revision
2026-01-16 07:26
Revised
2026-01-28 12:20
Publication Fee Transferred
2026-02-05 09:47
Second Decision by Editor
2026-02-28 02:32
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-28 06:21
Articles in Press
2026-02-28 06:21
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-12 03:40
Publish the Manuscript Online
2026-05-26 05:34
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Clinical Trials Study
Article Title Effects of Lactiplantibacillus plantarum 299v and Lactiplantibacillus plantarum GOS42 on gastrointestinal symptoms in healthy adults with occasional constipation
Manuscript Source Unsolicited Manuscript
All Author List Gunilla Önning, Christina Skovgaard Vegge, Caroline Montelius, Erin Diane Lewis, Huda Al-Wahsh, Marc Moulin, David Cecil Crowley and Najla Guthrie
ORCID
Author(s) ORCID Number
Gunilla Önning http://orcid.org/0000-0001-9122-8964
Christina Skovgaard Vegge http://orcid.org/0000-0003-4043-9598
Caroline Montelius http://orcid.org/0000-0001-7358-6098
Erin Diane Lewis http://orcid.org/0000-0002-1760-3073
Huda Al-Wahsh http://orcid.org/0000-0002-8576-686X
Marc Moulin http://orcid.org/0000-0001-6654-4914
Funding Agency and Grant Number
Corresponding Author Gunilla Önning, Adjunct Professor, Research and Development, Probi AB, Ideongatan 1A, Lund 22370, Sweden. gunilla.onning@probi.com
Key Words Occasional constipation; Stool frequency; Gut transit time; Bristol Stool Scale; Flatulence; Probiotics
Core Tip The strain Lactiplantibacillus plantarum (L. plantarum) 299v (Lp299v) has previously been shown to have positive effects on irritable bowel syndrome. For the first time, a randomized, double-blind, placebo-controlled study has evaluated the effects of Lp299v, together with a small amount of a secondary strain (L. plantarum GOS42), on constipation in otherwise healthy subjects. Supplementation of these two probiotic strains for eight weeks had a significant positive effect compared to placebo on various constipation-related symptoms such as number of weekly bowel movements (BMs), stool consistency, percentage of stools with hard/lumpy consistency, flatulence, and satisfaction with BM regularity.
Publish Date 2026-05-26 05:34
Citation

Önning G, Vegge CS, Montelius C, Lewis ED, Al-Wahsh H, Moulin M, Crowley DC, Guthrie N. Effects of Lactiplantibacillus plantarum 299v and Lactiplantibacillus plantarum GOS42 on gastrointestinal symptoms in healthy adults with occasional constipation. World J Gastroenterol 2026; 32(21): 117959

URL https://www.wjgnet.com/1007-9327/full/v32/i21/117959.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i21.117959
Full Article (PDF) WJG-32-117959-with-cover.pdf
CONSORT 2010 Statement 117959-CONSORT-2010-statement.pdf
Manuscript File 117959_Auto_Edited_110924.docx
Answering Reviewers 117959-answering-reviewers.pdf
Audio Core Tip 117959-audio.m4a
Biostatistics Review Certificate 117959-biostatistics-statement.pdf
Clinical Trial Registration Statement 117959-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 117959-conflict-of-interest-statement.pdf
Copyright License Agreement 117959-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 117959-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 117959-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 117959-non-native-speakers.pdf
Peer-review Report 117959-peer-reviews.pdf
Scientific Misconduct Check 117959-scientific-misconduct-check.png
Scientific Editor Work List 117959-scientific-editor-work-list.pdf
CrossCheck Report 117959-crosscheck-report.pdf