BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
8/11/2026 6:12:03 AM | Browse: 3 | Download: 0
 |
Received |
|
2025-12-22 09:07 |
|
Peer-Review Started |
|
2025-12-22 09:07 |
|
First Decision by Editorial Office Director |
|
2026-01-22 08:57 |
|
Return for Revision |
|
2026-01-22 08:57 |
|
Revised |
|
2026-02-04 10:41 |
|
Publication Fee Transferred |
|
2026-02-05 21:37 |
|
Second Decision by Editor |
|
2026-04-27 02:30 |
 |
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2026-04-27 07:12 |
|
Articles in Press |
|
2026-04-27 07:12 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2026-08-05 00:40 |
|
Publish the Manuscript Online |
|
2026-08-11 06:12 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Naringenin pretreatment attenuates hepatic ischemia-reperfusion injury by activating the PI3K-Akt signaling pathway
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jian-Sen Lu, Hong-Liang Liang, De-Cheng Chen, Hao Pan, Tian Han, Wei-Ye Zhang, Meng Fan, Wen Hou and Zhong-Yang Shen |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Tianjin City |
23JCZDJC01070 |
| Tianjin Key Medical Discipline Construction Project |
TJYXZDXK-3-006A, TJYXZDXK-3-005A |
| National Natural Science Foundation of China |
82241219 |
| National Major Scientific Research Instrument Development Project of China |
82127808 |
|
| Corresponding Author |
Zhong-Yang Shen, Tianjin Organ Transplantation Research Center, Institute of Transplantation Medicine, Tianjin First Central Hospital, Nankai University, No. 94 Fukang Road, Nankai District, Tianjin 300071, China. zhongyangshen@nankai.edu.cn |
| Key Words |
Hepatic ischemia-reperfusion injury; Naringenin; Phosphatidylinositol 3-kinase-protein kinase B signaling pathway; Oxidative stress; Apoptosis; Inflammatory response |
| Core Tip |
The specific protective effects and underlying molecular mechanisms in hepatic ischemia-reperfusion injury remain to be systematically elucidated. This study demonstrates that naringenin protects the liver from ischemia-reperfusion injury by inhibiting oxidative stress, inflammatory response, and hepatocyte apoptosis, with the phosphatidylinositol 3-kinase-protein kinase B signaling pathway serving as a key regulatory axis. |
| Publish Date |
2026-08-11 06:12 |
| Citation |
Lu JS, Liang HL, Chen DC, Pan H, Han T, Zhang WY, Fan M, Hou W, Shen ZY. Naringenin pretreatment attenuates hepatic ischemia-reperfusion injury by activating the PI3K-Akt signaling pathway. World J Gastroenterol 2026; 32(33): 117979
|
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i33/117979.htm |
| DOI |
https://doi.org/10.3748/wjg.117979 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
