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5/21/2026 7:49:50 AM | Browse: 1 | Download: 0
Publication Name World Journal of Critical Care Medicine
Manuscript ID 117985
Country United States
Received
2025-12-22 07:06
Peer-Review Started
2025-12-22 07:06
First Decision by Editorial Office Director
2025-12-31 08:21
Return for Revision
2025-12-31 08:21
Revised
2026-01-08 16:42
Publication Fee Transferred
Second Decision by Editor
2026-01-27 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-27 08:29
Articles in Press
2026-01-27 08:29
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-04-28 07:32
Publish the Manuscript Online
2026-05-21 07:49
ISSN 2220-3141(online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Meta-Analysis
Article Title Surgical fecal diversion vs non-diversion in perineal necrotizing soft tissue infections: A systematic review and meta-analysis
Manuscript Source Invited Manuscript
All Author List Marcelo Augusto Fontenelle Ribeiro Junior, Sharon M Henry, Husna Irfan Thalib, Sariya Khan, Agata Grochowska-Krystman, Lucas Fontenelle Vieira, Sachin Reddi and Rafael Dib Possiedi
ORCID
Author(s) ORCID Number
Marcelo Augusto Fontenelle Ribeiro Junior http://orcid.org/0000-0001-9826-4722
Sharon M Henry http://orcid.org/0000-0002-3032-5880
Husna Irfan Thalib http://orcid.org/0009-0009-6361-6586
Sariya Khan http://orcid.org/0009-0003-9809-872X
Agata Grochowska-Krystman http://orcid.org/0009-0005-0158-8066
Lucas Fontenelle Vieira http://orcid.org/0009-0009-1825-0562
Sachin Reddi http://orcid.org/0000-0002-0348-7606
Rafael Dib Possiedi http://orcid.org/0000-0002-3678-7920
Funding Agency and Grant Number
Corresponding Author Marcelo Augusto Fontenelle Ribeiro Junior, Director, FACS, Full Professor, MD, PhD, Department of Surgery, R Adams Cowley Shock Trauma Center, University of Maryland, 22 S Greene St-Baltimore, Baltimore, MD 21201, United States. drmribeiro@gmail.com
Key Words Nonsurgical fecal diversion; Perianal sepsis; Flexible fecal management system; Flexi-seal; Colostomy, surgical fecal diversion; Fournier’s gangrene; Fecal incontinence catheter; Evacuation management; Necrotizing fasciitis
Core Tip This systematic review and meta-analysis of thirty-six studies found no consistent differences between non-diversion and surgical fecal diversion (SFD) in mortality, intensive care unit admission or the number of surgical procedures. Hospital length of stay showed significant heterogeneity, with sensitivity analysis favoring non-diversion after exclusion of one outlier study. Overall certainty of evidence was very low, mainly due to confounding by indication and inconsistent group definitions. These findings do not demonstrate a clear overall advantage of routine SFD and support the need for standardized criteria and prospective studies in Perineal necrotizing soft tissue infections.
Publish Date 2026-05-21 07:49
Citation

Ribeiro Junior MAF, M Henry S, Thalib HI, Khan S, Grochowska-Krystman A, Fontenelle Vieira L, Reddi S, Dib Possiedi R. Surgical fecal diversion vs non-diversion in perineal necrotizing soft tissue infections: A systematic review and meta-analysis. World J Crit Care Med 2026; 15(2): 117985

URL https://www.wjgnet.com/2220-3141/full/v15/i2/117985.htm
DOI https://dx.doi.org/10.5492/wjccm.v15.i2.117985
Full Article (PDF) WJCCM-15-117985-with-cover.pdf
PRISMA 2009 Checklist 117985-PRISMA-2009-Checklist.pdf
Manuscript File 117985_Auto_Edited_072713.docx
Answering Reviewers 117985-answering-reviewers.pdf
Audio Core Tip 117985-audio.m4a
Biostatistics Review Certificate 117985-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 117985-conflict-of-interest-statement.pdf
Copyright License Agreement 117985-copyright-assignment.pdf
Supplementary Material 117985-supplementary-material.pdf
Peer-review Report 117985-peer-reviews.pdf
Scientific Misconduct Check 117985-scientific-misconduct-check.png
Scientific Editor Work List 117985-scientific-editor-work-list.pdf
CrossCheck Report 117985-crosscheck-report.pdf