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Articles Published Processes
4/21/2026 8:57:44 AM | Browse: 12 | Download: 27
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Received |
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2025-12-22 08:55 |
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Peer-Review Started |
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2025-12-22 08:55 |
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First Decision by Editorial Office Director |
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2026-01-06 09:05 |
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Return for Revision |
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2026-01-06 09:05 |
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Revised |
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2026-01-19 15:17 |
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Publication Fee Transferred |
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2026-01-22 02:38 |
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Second Decision by Editor |
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2026-02-13 02:36 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-13 02:48 |
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Articles in Press |
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2026-02-13 02:48 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-04-10 06:28 |
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Publish the Manuscript Online |
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2026-04-21 08:57 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Tumor necrosis factor ligand superfamily member 13B mutation-associated chronic cholangitis with cirrhosis: A case report and literature review
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ying Zhou, Qi-Jiao Cheng, Ming-Xing Liang, Su-Qun Li, Yu-Zhi Su, Yong-Ming Cai, Zong-Qin Pan, Yu-Xin Xie, Ying-Hua Chen and Yi-Huai He |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Science and Technology Planning Projects of Guizhou Province |
QKHJC-MS(2025)384, and QKHJC-MS(2025)392 |
| Health Research Project of Guizhou Province |
gzwkj2024-103, and 2024GZWJXM0435 |
| Scientific Research Project of the Guizhou Provincial Bureau of Traditional Chinese Medicine |
QZYY-2023-021 |
| Beijing Liver and Gallbladder Mutual Aid Public Welfare Foundation Artificial Liver Special Fund |
iGandanF-1082024-RGG018 |
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| Corresponding Author |
Yi-Huai He, MD, Department of Infectious Diseases, Affiliated Hospital of Zunyi Medical University, No. 201 Dalian Street, Zunyi 563000, Guizhou Province, China. 993565989@qq.com |
| Key Words |
Autoimmune liver disease; Chronic cholangitis; TNFRSF13B gene; B cell homeostasis; Case report |
| Core Tip |
Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B/TACI) maintains immune homeostasis through bidirectional regulation of B cell function. This case report presents a case where a TNFRSF13B mutation that may impair TACI’s negative regulatory control over B cell activity, causing B cell hyperactivation, sustained local inflammatory responses, and chronic cholangitis progressing to cirrhosis. This finding provides a novel immunogenetic perspective for understanding certain autoimmune liver diseases of unknown etiology. |
| Publish Date |
2026-04-21 08:57 |
| Citation |
Zhou Y, Cheng QJ, Liang MX, Li SQ, Su YZ, Cai YM, Pan ZQ, Xie YX, Chen YH, He YH. Tumor necrosis factor ligand superfamily member 13B mutation-associated chronic cholangitis with cirrhosis: A case report and literature review. World J Hepatol 2026; 18(4): 117993 |
| URL |
https://www.wjgnet.com/1948-5182/full/v18/i4/117993.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v18.i4.117993 |
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