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5/19/2026 7:13:10 AM | Browse: 0 | Download: 0
Publication Name World Journal of Cardiology
Manuscript ID 118011
Country United States
Received
2025-12-22 08:11
Peer-Review Started
2025-12-22 08:12
First Decision by Editorial Office Director
2025-12-31 07:57
Return for Revision
2025-12-31 07:57
Revised
2026-01-17 04:11
Publication Fee Transferred
Second Decision by Editor
2026-03-23 02:49
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-23 11:32
Articles in Press
2026-03-23 11:32
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-12 00:48
Publish the Manuscript Online
2026-05-19 07:13
ISSN 1949-8462 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Meta-Analysis
Article Title Efficacy of acetaminophen compared to ibuprofen for patent ductus arteriosus in preterm neonates: A systematic review and meta-analysis
Manuscript Source Invited Manuscript
All Author List Hakim Ullah Wazir, I M Khalid Reza, Maha Sajjad, Noora Inam, Tooba Fida, Noor Fatima, Aleena Sharif, Inayat Ullah, Sadaf Naz, Humaira, Muhammad Junaid Khan, Ali Dad, Hafiz Muhammad Moaaz Sajid, Usha Kumari and Salim Surani
ORCID
Author(s) ORCID Number
Hakim Ullah Wazir http://orcid.org/0009-0004-4653-3803
Maha Sajjad http://orcid.org/0009-0000-8753-6681
Noor Fatima http://orcid.org/0009-0003-0987-0272
Usha Kumari http://orcid.org/0000-0001-9499-7056
Salim Surani http://orcid.org/0000-0001-7105-4266
Funding Agency and Grant Number
Corresponding Author Salim Surani, FACP, FCCP, MD, Professor, Department of Medicine, University of Houston, 4302 University Drive, Houston, TX 77004, United States. srsurani@hotmail.com
Key Words Patent ductus arteriosus; Acetaminophen; Ibuprofen; Preterm infants; Congenital heart disease
Core Tip Eighteen randomized controlled trials involving 1946 patients were included. Acetaminophen demonstrates comparable efficacy to ibuprofen with a more favorable safety profile, particularly regarding gastrointestinal bleeding and renal complications. This study suggests acetaminophen as first-line pharmacologic therapy in preterm infants with contraindications to nonsteroidal anti-inflammatory drugs or increased bleeding risk/renal dysfunction.
Publish Date 2026-05-19 07:13
Citation

Wazir HU, Reza IMK, Sajjad M, Inam N, Fida T, Fatima N, Sharif A, Ullah I, Naz S, H, Khan MJ, Dad A, Sajid HMM, Kumari U, Surani S. Efficacy of acetaminophen compared to ibuprofen for patent ductus arteriosus in preterm neonates: A systematic review and meta-analysis. World J Cardiol 2026; 18(5): 118011

URL https://www.wjgnet.com/1949-8462/full/v18/i5/118011.htm
DOI https://dx.doi.org/10.4330/wjc.v18.i5.118011
Full Article (PDF) WJC-18-118011-with-cover.pdf
PRISMA 2009 Checklist 118011-PRISMA-2009-Checklist.pdf
Manuscript File 118011_Auto_Edited_092059.docx
Answering Reviewers 118011-answering-reviewers.pdf
Audio Core Tip 118011-audio.m4a
Biostatistics Review Certificate 118011-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 118011-conflict-of-interest-statement.pdf
Copyright License Agreement 118011-copyright-assignment.pdf
Supplementary Material 118011-supplementary-material.pdf
Peer-review Report 118011-peer-reviews.pdf
Scientific Misconduct Check 118011-scientific-misconduct-check.png
Scientific Editor Work List 118011-scientific-editor-work-list.pdf
CrossCheck Report 118011-crosscheck-report.pdf