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Articles Published Processes
5/29/2026 7:26:45 AM | Browse: 2 | Download: 16
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Received |
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2025-12-26 02:07 |
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Peer-Review Started |
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2025-12-26 02:07 |
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First Decision by Editorial Office Director |
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2026-02-02 04:06 |
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Return for Revision |
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2026-02-02 04:06 |
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Revised |
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2026-02-13 10:42 |
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Publication Fee Transferred |
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2026-02-15 03:49 |
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Second Decision by Editor |
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2026-03-09 02:46 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-09 08:03 |
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Articles in Press |
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2026-03-09 08:03 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-05-15 01:49 |
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Publish the Manuscript Online |
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2026-05-29 07:26 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Sex-specific differences in the efficacy and prognosis of 5-aminosalicylic acid therapy for ulcerative colitis: A 20-year retrospective cohort study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhao-Shi Liu, Hao Tang, Hui-Min Zhang, Xiao-Yin Bai, Hong Yang, Xiao-Feng Li and Jia-Ming Qian |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Health Research and Special Projects Grant of China |
No. 201002020 |
| CAMS Innovation Fund for Medical Sciences |
No. 2016-I2M-3-001 |
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| Corresponding Author |
Jia-Ming Qian, Chief Physician, MD, Professor, Department of Gastroenterology, Peking Union Medical College Hospital, No. 1 Shuaifuyuan, Dongcheng District, Beijing 100730, China. qianjm@pumch.cn |
| Key Words |
Ulcerative colitis; Inflammatory bowel disease; 5-aminosalicylic acid; Sex-specific differences; Efficacy; Prognosis; Endoscopic mucosal healing; Colectomy; Surgery |
| Core Tip |
Real-world data concerning sex-specific differences in the response to and long-term outcomes of 5-aminosalicylic acid (5-ASA) therapy for ulcerative colitis (UC) in large-scale UC cohorts are lacking. This retrospective study analyzed 354 patients receiving 5-ASA treatment after 1:1 propensity score matching. Male patients had an increased chance of frequent UC flare-ups, less frequent and delayed endoscopic mucosal healing, and a higher risk of surgery. These findings emphasize the need for sex-adapted therapeutic strategies to optimize 5-ASA utilization and improve individualized UC management. |
| Publish Date |
2026-05-29 07:26 |
| Citation |
Liu ZS, Tang H, Zhang HM, Bai XY, Yang H, Li XF, Qian JM. Sex-specific differences in the efficacy and prognosis of 5-aminosalicylic acid therapy for ulcerative colitis: A 20-year retrospective cohort study. World J Gastroenterol 2026; 32(22): 118036 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i22/118036.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i22.118036 |
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