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Articles Published Processes
4/21/2026 8:57:43 AM | Browse: 3 | Download: 1
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Received |
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2025-12-25 01:25 |
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Peer-Review Started |
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2025-12-25 01:26 |
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First Decision by Editorial Office Director |
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2026-01-06 09:06 |
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Return for Revision |
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2026-01-06 09:06 |
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Revised |
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2026-01-08 19:58 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-02-05 02:37 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-05 07:18 |
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Articles in Press |
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2026-02-05 07:18 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-04-10 06:26 |
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Publish the Manuscript Online |
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2026-04-21 08:57 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Meta-Analysis |
| Article Title |
Diagnostic accuracy of blood-based non-invasive tests for prediction of varices in pediatric portal-hypertension: A systematic review and meta-analysis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Kalpana Panda, Devi P Dash, Girish K Pati, Arjun Maria and Vipul Gautam |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Kalpana Panda, Associate Professor, Department Pediatric Gastroenterology and Hepatology, Institute of Medical Sciences and SUM Hospital, Kalinga Nagar, Bhubaneshwar 751003, Odisha, India. drkalpanapanda@gmail.com |
| Key Words |
Pediatric; Portal hypertension; Platelet count; Aspartate aminotransferase to platelet ratio index; Liver cirrhosis; Varices; Clinically significant varices; Non-invasive tests |
| Core Tip |
Blood-based non-invasive tests offer a pragmatic approach for risk stratification of varices in children with portal hypertension. This meta-analysis reveals that commonly used indices, such as aminotransferase-to-platelet ratio index, platelet count, demonstrate moderate diagnostic accuracy and may help identify children at lower risk who could safely defer immediate endoscopic surveillance. Their advantages include wide availability, low cost, and ease of repeat testing, making them particularly relevant in resource-limited settings. However, substantial heterogeneity, variability in applied cut-off thresholds, and low-to-moderate certainty of evidence limit their reliability as standalone tools. Prospective pediatric studies with standardised and aetiology-specific cut-offs are essential before implementing routine guidelines. |
| Publish Date |
2026-04-21 08:57 |
| Citation |
Panda K, Dash DP, Pati GK, Maria A, Gautam V. Diagnostic accuracy of blood-based non-invasive tests for prediction of varices in pediatric portal-hypertension: A systematic review and meta-analysis. World J Hepatol 2026; 18(4): 118038 |
| URL |
https://www.wjgnet.com/1948-5182/full/v18/i4/118038.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v18.i4.118038 |
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