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7/24/2026 7:03:47 AM | Browse: 2 | Download: 0
Publication Name World Journal of Hepatology
Manuscript ID 118048
Country China
Received
2025-12-23 06:33
Peer-Review Started
2025-12-23 06:34
First Decision by Editorial Office Director
2026-01-07 10:22
Return for Revision
2026-01-08 00:52
Revised
2026-01-16 03:25
Publication Fee Transferred
Second Decision by Editor
2026-02-05 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-05 09:40
Articles in Press
2026-02-05 09:40
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-14 07:13
Publish the Manuscript Online
2026-07-24 07:03
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Opinion Review
Article Title Efficacy and mechanism of Xing-Pi-Qing-Gan decoction in treating alcoholic liver disease
Manuscript Source Invited Manuscript
All Author List Hui Gou, Ping Chen, Jin-Wei Li and Wen-Bing Wu
ORCID
Author(s) ORCID Number
Wen-Bing Wu http://orcid.org/0000-0002-8132-5100
Funding Agency and Grant Number
Corresponding Author Wen-Bing Wu, Lecturer, PhD, Department of Biochemistry and Molecular Biology, School of Basical Medical Sciences, Southwest Medical University, No. 1, Section 1, Xianglin Road, Longma Tan District, Luzhou 646000, Sichuan Province, China. wuwenbing5@vip.163.com
Key Words Alcoholic liver disease; Xing-Pi-Qing-Gan decoction; DNA damage-inducible transcript 3; Nuclear factor erythroid 2-related factor 2/heme oxygenase-1 signaling pathway; Oxidative stress
Core Tip This letter reviews Huang et al.’s study on Xing-Pi-Qing-Gan decoction (XPQG) for alcoholic liver disease, demonstrating the mechanism by which XPQG inhibits liver injury by inhibiting DNA damage-inducible transcript 3 (DDIT3) and activating nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) through multiple sets of experiments. On the basis of affirming the scientific evidence of traditional Chinese medicine in the treatment of metabolic liver disease, this article discusses the potential regulation mechanism of "gut-liver axis" of this prescription, and puts forward the necessity of establishing a standardized drug quality control system in the future clinical transformation.
Publish Date 2026-07-24 07:03
Citation

Gou H, Chen P, Li JW, Wu WB. Efficacy and mechanism of Xing-Pi-Qing-Gan decoction in treating alcoholic liver disease. World J Hepatol 2026; 18(7): 118048

URL https://www.wjgnet.com/1948-5182/full/v18/i7/118048.htm
DOI https://doi.org/10.4254/wjh.118048
Full Article (PDF) WJH-18-118048-with-cover.pdf
Manuscript File 118048_Auto_Edited_005628.docx
Answering Reviewers 118048-answering-reviewers.pdf
Audio Core Tip 118048-audio.mp3
Conflict-of-Interest Disclosure Form 118048-conflict-of-interest-statement.pdf
Copyright License Agreement 118048-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 118048-non-native-speakers.pdf
Peer-review Report 118048-peer-reviews.pdf
Scientific Misconduct Check 118048-scientific-misconduct-check.png
Scientific Editor Work List 118048-scientific-editor-work-list.pdf
CrossCheck Report 118048-crosscheck-report.pdf