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4/2/2026 6:31:32 AM | Browse: 1 | Download: 0
Publication Name World Journal of Clinical Cases
Manuscript ID 118053
Country India
Received
2025-12-23 06:36
Peer-Review Started
2025-12-23 06:36
First Decision by Editorial Office Director
2026-01-28 08:40
Return for Revision
2026-01-28 08:40
Revised
2026-02-10 04:45
Publication Fee Transferred
Second Decision by Editor
2026-03-06 02:32
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-06 06:05
Articles in Press
2026-03-06 06:05
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-23 00:54
Publish the Manuscript Online
2026-04-02 06:31
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pediatrics
Manuscript Type Randomized Controlled Trial
Article Title Comparative evaluation of anesthetic efficacy of articaine vs lignocaine during root canal therapy in hypomineralized second primary molars
Manuscript Source Invited Manuscript
All Author List Olando Kevin D’Souza
ORCID
Author(s) ORCID Number
Olando Kevin D’Souza http://orcid.org/0009-0002-4420-696X
Funding Agency and Grant Number
Corresponding Author Olando Kevin D’Souza, Consultant, Department of Pedodontics and Preventive Dentistry, Goa Dental College and Hospital, Near Goa Medical College, Bambolim 403202, Goa, India. olandokevindsouza@gmail.com
Key Words Local anesthesia; Articaine; Lignocaine; Hypomineralized second primary molars; Efficacy
Core Tip Achieving effective pulpal anesthesia in hypomineralized second primary molars is often challenging with conventional local anesthetics. This split-mouth clinical study demonstrates that 4% articaine provides superior intraoperative anesthetic efficacy compared with 2% lignocaine during root canal treatment of hypomineralized second primary molars, particularly during access cavity preparation and canal instrumentation. While both agents showed comparable discomfort during injection, articaine achieved more profound and consistent pulpal anesthesia. The findings underscore the clinical importance of selecting anesthetic agents with enhanced tissue penetration for hypomineralized teeth and provide evidence-based guidance for improving pain control and treatment outcomes in pediatric endodontic practice.
Publish Date 2026-04-02 06:31
Citation

D’Souza OK. Comparative evaluation of anesthetic efficacy of articaine vs lignocaine during root canal therapy in hypomineralized second primary molars. World J Clin Cases 2026; 14(10): 118053

URL https://www.wjgnet.com/2307-8960/full/v14/i10/118053.htm
DOI https://dx.doi.org/10.12998/wjcc.v14.i10.118053
Full Article (PDF) WJCC-14-118053-with-cover.pdf
CONSORT 2010 Statement 118053-CONSORT-2010-statement.pdf
Manuscript File 118053_Auto_Edited_034422.docx
Answering Reviewers 118053-answering-reviewers.pdf
Audio Core Tip 118053-audio.m4a
Biostatistics Review Certificate 118053-biostatistics-statement.pdf
Clinical Trial Registration Statement 118053-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 118053-conflict-of-interest-statement.pdf
Copyright License Agreement 118053-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 118053-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 118053-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 118053-non-native-speakers.pdf
Peer-review Report 118053-peer-reviews.pdf
Scientific Misconduct Check 118053-scientific-misconduct-check.png
Scientific Editor Work List 118053-scientific-editor-work-list.pdf
CrossCheck Report 118053-crosscheck-report.pdf