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Articles Published Processes
5/20/2026 8:53:16 AM | Browse: 2 | Download: 11
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Received |
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2025-12-23 09:10 |
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Peer-Review Started |
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2025-12-23 09:10 |
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First Decision by Editorial Office Director |
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2026-01-28 09:24 |
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Return for Revision |
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2026-01-29 11:17 |
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Revised |
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2026-02-12 08:09 |
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Publication Fee Transferred |
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2026-02-13 04:31 |
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Second Decision by Editor |
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2026-03-26 02:35 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-26 07:29 |
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Articles in Press |
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2026-03-26 07:29 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-05-11 01:11 |
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Publish the Manuscript Online |
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2026-05-20 08:53 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Integrative & Complementary Medicine |
| Manuscript Type |
Minireviews |
| Article Title |
DNA methylation in gastric precancerous lesions: Molecular mechanisms and clinical translation
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Si-Hui Zeng, Yu-Qi Wu, Wei-Jian Zhang, Yi-Tian Wang, Lin Xu and Shao-Ju Guo |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
82374348 |
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| Corresponding Author |
Shao-Ju Guo, Professor, Department of Spleen and Stomach Diseases, Shenzhen Hospital of Traditional Chinese Medicine, Fuhua Road, Shenzhen 518000, Guangdong Province, China. gsjgsjgsj2024@163.com |
| Key Words |
DNA methylation; Gastric precancerous lesions; Epigenetic biomarkers; Helicobacter pylori; Intestinal metaplasia; Risk stratification; Early detection of cancer; Epigenetic therapy; Chemoprevention; Molecular mechanisms |
| Core Tip |
DNA methylation is a pivotal epigenetic driver in gastric precarcinogenesis, orchestrating the stepwise progression from precancerous lesions to cancer. Clinically, methylation biomarkers enable non-invasive early detection, risk stratification, and prognostic assessment. Therapeutically, targeting methylation-regulating enzymes and implementing methylation-guided chemoprevention represent promising precision intervention strategies. |
| Publish Date |
2026-05-20 08:53 |
| Citation |
Zeng SH, Wu YQ, Zhang WJ, Wang YT, Xu L, Guo SJ. DNA methylation in gastric precancerous lesions: Molecular mechanisms and clinical translation. World J Clin Oncol 2026; 17(5): 118073 |
| URL |
https://www.wjgnet.com/2218-4333/full/v17/i5/118073.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v17.i5.118073 |
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