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3/16/2026 9:13:12 AM | Browse: 5 | Download: 0
Publication Name World Journal of Clinical Cases
Manuscript ID 118134
Country Greece
Received
2025-12-25 01:30
Peer-Review Started
2025-12-25 01:31
First Decision by Editorial Office Director
2026-01-09 07:48
Return for Revision
2026-01-09 07:48
Revised
2026-01-17 10:35
Publication Fee Transferred
Second Decision by Editor
2026-02-12 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-12 04:06
Articles in Press
2026-02-12 04:06
Edit the Manuscript by Language Editor
2026-02-15 17:29
Typeset the Manuscript
2026-03-06 03:40
Publish the Manuscript Online
2026-03-16 09:13
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type Case Report
Article Title Value of whole-body magnetic resonance imaging on progressive axial fusion and chronic non-bacterial osteomyelitis in paediatric Crohn’s disease: A case report
Manuscript Source Invited Manuscript
All Author List George Triantafyllou, Spyridon Prountzos, Konstantina Bolou, Nikolaos-Achilleas Arkoudis, Konstantina Liontou, Maria Piagkou, Lampros Fotis and Olympia Papakonstantinou
ORCID
Author(s) ORCID Number
George Triantafyllou http://orcid.org/0009-0001-0122-2436
Spyridon Prountzos http://orcid.org/0000-0001-9651-8338
Nikolaos-Achilleas Arkoudis http://orcid.org/0000-0002-0783-5700
Olympia Papakonstantinou http://orcid.org/0000-0003-0331-207X
Funding Agency and Grant Number
Corresponding Author George Triantafyllou, Department of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, 75 Mikras Asias Street, Goudi, Athens 11527, Attikí, Greece. georgerose406@gmail.com
Key Words Whole-body magnetic resonance imaging; Spondyloarthropathy; Chronic non-bacterial osteomyelitis; Crohn’s disease; Case report
Core Tip Pediatric Crohn’s disease can coexist with chronic non-bacterial osteomyelitis and spondyloarthropathy, creating a severe autoinflammatory phenotype linked to NOD2 variants. This case demonstrates that persistent skeletal pain in inflammatory bowel disease patients requires a high index of suspicion for multifocal bone involvement. Whole-body magnetic resonance imaging should be considered for mapping total inflammatory load and preventing irreversible structural damage, such as cervical fusion. Management often necessitates a multi-target approach, utilizing JAK inhibitors and bisphosphonates to address refractory systemic inflammation and preserve skeletal integrity.
Publish Date 2026-03-16 09:13
Citation

Triantafyllou G, Prountzos S, Bolou K, Arkoudis NA, Liontou K, Piagkou M, Fotis L, Papakonstantinou O. Value of whole-body magnetic resonance imaging on progressive axial fusion and chronic non-bacterial osteomyelitis in paediatric Crohn’s disease: A case report. World J Clin Cases 2026; 14(8): 118134

URL https://www.wjgnet.com/2307-8960/full/v14/i8/118134.htm
DOI https://dx.doi.org/10.12998/wjcc.v14.i8.118134
Full Article (PDF) WJCC-14-118134-with-cover.pdf
CARE Checklist–2016 118134-CARE-Checklist-2016.pdf
Manuscript File 118134_Auto_Edited_082052.docx
Answering Reviewers 118134-answering-reviewers.pdf
Audio Core Tip 118134-audio.m4a
Conflict-of-Interest Disclosure Form 118134-conflict-of-interest-statement.pdf
Copyright License Agreement 118134-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 118134-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 118134-non-native-speakers.pdf
Peer-review Report 118134-peer-reviews.pdf
Scientific Misconduct Check 118134-scientific-misconduct-check.png
Scientific Editor Work List 118134-scientific-editor-work-list.pdf
CrossCheck Report 118134-crosscheck-report.pdf