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Articles Published Processes
8/3/2026 1:23:59 AM | Browse: 2 | Download: 0
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Received |
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2025-12-29 01:22 |
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Peer-Review Started |
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2025-12-29 01:23 |
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First Decision by Editorial Office Director |
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2026-01-23 08:17 |
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Return for Revision |
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2026-01-23 08:17 |
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Revised |
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2026-02-20 13:51 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-04-03 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-04-03 05:09 |
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Articles in Press |
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2026-04-03 05:09 |
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Edit the Manuscript by Language Editor |
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2026-04-11 04:04 |
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Typeset the Manuscript |
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2026-07-23 03:30 |
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Publish the Manuscript Online |
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2026-08-03 01:23 |
| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pediatrics |
| Manuscript Type |
Review |
| Article Title |
Interface between inborn errors of immunity and rheumatological disorders in children: A pediatrician’s conundrum
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Abarna Thangaraj, Ridhima Aggarwal, Soumyadeep Sarkar and Rakesh Kumar Pilania |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
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| Corresponding Author |
Rakesh Kumar Pilania, Pediatric Allergy Immunology Unit, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research, APC 4A, 4127, Advanced pediatrics, Chandigarh 160012, India. kumarpilania007@gmail.com |
| Key Words |
Inborn errors of immunity; Rheumatology; Monogenic disease; Immune dysregulation; Children |
| Core Tip |
Rheumatological disorders in children may represent the initial manifestation of inborn errors of immunity (IEIs), a rapidly expanding group of monogenic immune dysregulation syndromes. Increasing overlap exists between IEIs and pediatric rheumatologic diseases, including arthritis, vasculitis, cytopenias, lupus, macrophage activation syndrome, and polyautoimmunity. Early age of onset, atypical or severe disease, recurrent infections, multi-organ involvement, and poor response to standard therapy are key red flags. Early recognition and genetic diagnosis enable precision-based targeted therapies, significantly improving outcomes. |
| Publish Date |
2026-08-03 01:23 |
| Citation |
Thangaraj A, Aggarwal R, Sarkar S, Pilania RK. Interface between inborn errors of immunity and rheumatological disorders in children: A pediatrician’s conundrum. World J Clin Pediatr 2026; 15(3): 118174
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| URL |
https://www.wjgnet.com/2219-2808/full/v15/i3/118174.htm |
| DOI |
https://doi.org/10.5409/wjcp.118174 |
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