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Articles Published Processes
11/10/2026 1:43:55 AM | Browse: 1 | Download: 0
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Received |
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2025-12-26 02:49 |
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Peer-Review Started |
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2025-12-26 02:49 |
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First Decision by Editorial Office Director |
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2026-01-20 08:21 |
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Return for Revision |
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2026-01-20 08:21 |
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Revised |
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2026-02-06 13:34 |
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Publication Fee Transferred |
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2026-02-13 11:32 |
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Second Decision by Editor |
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2026-10-08 07:09 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-10-08 09:13 |
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Articles in Press |
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2026-10-08 09:13 |
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Edit the Manuscript by Language Editor |
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2026-10-15 21:20 |
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Typeset the Manuscript |
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2026-11-05 00:27 |
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Publish the Manuscript Online |
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2026-11-10 01:43 |
| ISSN |
2218-5836 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Basic Study |
| Article Title |
Osteoreparative potential of nanofibrillated cellulose, xenograft, and butvar-phenolic adhesive-based composite
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Berik E Tuleubayev, Bakhtiyar K Makhatov, Vladimir A Vinokurov, Yevgeniy K Kamyshanskiy, Yekaterina Y Kossilova, Saule B Akhmetova, Amina A Koshanova, Marat Z Davletbaev and Marietta G Arutyunyan |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Science Committee of the Ministry of Education and Science of the Republic of Kazakhstan |
АР19678427 |
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| Corresponding Author |
Bakhtiyar K Makhatov, Doctorate Student, Department of Surgery Diseases, NPJSC "Karaganda Medical University", Gogol street, 40, Karaganda 100000, Kazakhstan. mahatov@qmu.kz |
| Key Words |
Bone regeneration; Biocomposite; Nanofibrilated cellulose; Bone graft; Marburg bone bank system |
| Core Tip |
This preclinical study investigates a tricomponent bone substitute-nanofibrillated cellulose, thermally disinfected bone xenograft (Marburg Bone Bank System), and polyvinyl butyral-phenolic (Butvar-phenolic) adhesive-implanted as a uniformly premixed composite in a rat femoral diaphyseal defect model. The mixed composite demonstrated superior cortical plate regeneration on days 30 and 60, significantly reduced intramedullary migration, and more pronounced scaffold remodeling compared with xenograft alone. In a Staphylococcus aureus-inoculated wound model, the composite markedly attenuated osteonecrosis and polymorphonuclear granulocyte infiltration. These results support its dual role as an osteoconductive/osteoinductive scaffold with inherent barrier resistance to infection-related bone injury. |
| Publish Date |
2026-11-10 01:43 |
| Citation |
Tuleubayev BE, Makhatov BK, Vinokurov VA, Kamyshanskiy YK, Kossilova YY, Akhmetova SB, Koshanova AA, Davletbaev MZ, Arutyunyan MG. Osteoreparative potential of nanofibrillated cellulose, xenograft, and butvar-phenolic adhesive-based composite. World J Orthop 2026; 17(11): 118182
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| URL |
https://www.wjgnet.com/2218-5836/full/v17/i11/118182.htm |
| DOI |
https://doi.org/10.5312/wjo.118182 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
