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Articles Published Processes
8/11/2026 6:12:03 AM | Browse: 8 | Download: 0
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Received |
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2025-12-29 06:24 |
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Peer-Review Started |
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2025-12-29 06:25 |
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First Decision by Editorial Office Director |
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2026-01-23 09:28 |
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Return for Revision |
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2026-01-23 09:28 |
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Revised |
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2026-02-25 17:13 |
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Publication Fee Transferred |
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2026-03-03 07:19 |
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Second Decision by Editor |
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2026-04-10 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-04-10 08:12 |
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Articles in Press |
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2026-04-10 08:12 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-08-05 00:42 |
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Publish the Manuscript Online |
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2026-08-11 06:12 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Observational Study |
| Article Title |
Urinary N1, N12-diacetylspermine as a potential tumor biomarker for gastric and colorectal cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hua-Zhen Zheng, Peng Wang, Hui-Jie Zheng, Zi-Qi Wang, Qi-Xin Li, Huan-Wei Chen, Huo-Qiang Chen and Qiu-Cheng Lei |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China (General Program) |
No. 82400651 |
| Foshan Science and Technology Innovation Project |
No. 2320001006781 |
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| Corresponding Author |
Qiu-Cheng Lei, Department of Hepatobiliary and Pancreatic Surgery, The First People’s Hospital of Foshan (Foshan Hospital Affiliated to Southern University of Science and Technology), School of Medicine, Southern University of Science and Technology, No. 81 Lingnan Avenue North, Foshan 528000, Guangdong Province, China. lqiuchenggd@163.com |
| Key Words |
N1, N12-diacetylspermine; Tumor biomarker; Gastric cancer; Colorectal cancer; Urinary N1, N12-diacetylspermine; Liquid biopsy |
| Core Tip |
Urinary N1, N12-diacetylspermine (DiAcSpm) was evaluated as a potential non-invasive biomarker for gastric and colorectal cancer. Levels were significantly elevated in cancer patients and showed moderate diagnostic value, which improved when combined with carcinoembryonic antigen. Urinary DiAcSpm levels decreased after chemotherapy in colorectal cancer patients, and high levels correlated with distant metastasis in gastric cancer patients. These findings support the potential of urinary DiAcSpm, though prospective studies in larger cohorts are warranted to confirm its clinical utility. |
| Publish Date |
2026-08-11 06:12 |
| Citation |
Zheng HZ, Wang P, Zheng HJ, Wang ZQ, Li QX, Chen HW, Chen HQ, Lei QC. Urinary N1, N12-diacetylspermine as a potential tumor biomarker for gastric and colorectal cancer. World J Gastroenterol 2026; 32(33): 118185
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| URL |
https://www.wjgnet.com/1007-9327/full/v32/i33/118185.htm |
| DOI |
https://doi.org/10.3748/wjg.118185 |
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