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6/15/2026 8:38:33 AM | Browse: 2 | Download: 0
Publication Name World Journal of Nephrology
Manuscript ID 118219
Country Italy
Received
2025-12-28 09:30
Peer-Review Started
2025-12-28 09:31
First Decision by Editorial Office Director
2026-01-14 08:22
Return for Revision
2026-01-14 08:22
Revised
2026-01-27 20:59
Publication Fee Transferred
Second Decision by Editor
2026-03-05 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-05 11:26
Articles in Press
2026-03-05 11:26
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-29 13:10
Publish the Manuscript Online
2026-06-15 08:38
ISSN 2220-6124 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Urology & Nephrology
Manuscript Type Minireviews
Article Title Slow continuous ultrafiltration and prolonged intermittent renal replacement therapy: Tailoring renal replacement therapy in intensive care unit
Manuscript Source Invited Manuscript
All Author List Guido Gembillo, Matteo Floris, Lorenzo Lo Cicero, Giuseppe Spadaro, Luca Soraci and Domenico Santoro
ORCID
Author(s) ORCID Number
Guido Gembillo http://orcid.org/0000-0003-4823-9910
Matteo Floris http://orcid.org/0000-0001-5557-9791
Luca Soraci http://orcid.org/0000-0002-0171-3358
Domenico Santoro http://orcid.org/0000-0002-7822-6398
Funding Agency and Grant Number
Corresponding Author Guido Gembillo, Unit of Nephrology and Dialysis, Department of Clinical and Experimental Medicine, AOU “G. Martino”, University of Messina, Via Consolare Valeria 1, Messina 98125, Italy. guidogembillo@live.it
Key Words Heart failure; Chronic kidney disease; Acute kidney injury; Diuretic resistance; Renal failure; Intensive care unit; Slow Continuous ultrafiltration; Prolonged intermittent renal replacement therapy
Core Tip Acute kidney injury in intensive care settings requires more than choosing a dialysis modality. An overall understanding of each patient’s fragility, priorities, and capacity for recovery is needed. Slow continuous ultrafiltration offers gentle decongestion for those burdened by volume overload, while prolonged intermittent renal replacement therapy provides steady support that preserves hemodynamic tolerance and allows meaningful time off therapy. Continuous treatments are essential when instability leaves no room for abrupt physiologic shifts. The central insight is that renal-replacement therapy succeeds when tailored to the patient’s evolving physiology, transforming a technical intervention into truly individualized organ support.
Publish Date 2026-06-15 08:38
Citation

Gembillo G, Floris M, Lo Cicero L, Spadaro G, Soraci L, Santoro D. Slow continuous ultrafiltration and prolonged intermittent renal replacement therapy: Tailoring renal replacement therapy in intensive care unit. World J Nephrol 2026; 15(2): 118219

URL https://www.wjgnet.com/2220-6124/full/v15/i2/118219.htm
DOI https://doi.org/10.5527/wjn.v15.i2.118219
Full Article (PDF) WJN-15-118219-with-cover.pdf
Manuscript File 118219_Auto_Edited-YJP.docx
Answering Reviewers 118219-answering-reviewers.pdf
Audio Core Tip 118219-audio.m4a
Conflict-of-Interest Disclosure Form 118219-conflict-of-interest-statement.pdf
Copyright License Agreement 118219-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 118219-non-native-speakers.pdf
Peer-review Report 118219-peer-reviews.pdf
Scientific Misconduct Check 118219-scientific-misconduct-check.png
Scientific Editor Work List 118219-scientific-editor-work-list.pdf
CrossCheck Report 118219-crosscheck-report.pdf