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6/16/2026 8:10:08 AM | Browse: 1 | Download: 0
Publication Name World Journal of Experimental Medicine
Manuscript ID 118228
Country Greece
Received
2025-12-31 02:34
Peer-Review Started
2025-12-31 02:34
First Decision by Editorial Office Director
2026-01-20 09:17
Return for Revision
2026-01-20 09:17
Revised
2026-01-22 12:08
Publication Fee Transferred
Second Decision by Editor
2026-02-04 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-04 09:18
Articles in Press
2026-02-04 09:18
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-04 02:07
Publish the Manuscript Online
2026-06-16 08:10
ISSN 2220-315x (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Correspondence
Article Title Letter to the Editor: Circadian and microbial misalignment in metabolic dysfunction-associated steatotic liver disease - mechanistic insights and chronotherapeutic potential
Manuscript Source Unsolicited Manuscript
All Author List Christos Savvidis and Ioannis Ilias
ORCID
Author(s) ORCID Number
Christos Savvidis http://orcid.org/0000-0002-0188-1685
Ioannis Ilias http://orcid.org/0000-0001-5718-7441
Funding Agency and Grant Number
Corresponding Author Ioannis Ilias, Director, MD, PhD, Department of Endocrinology, Hippocration General Hospital, No. 63 Evrou Street, Athens 11527, Greece. iiliasmd@yahoo.com
Key Words Circadian disruption; Steatotic liver disease; Time-restricted eating; Melatonin; Chronotherapy
Core Tip The gut-liver axis is a rhythmic system regulated by a bidirectional interaction between host clocks and the gut microbiota. Social jetlag disrupts the timing of metabolites and by compromising the intestinal barrier, which exacerbates metabolic injury in metabolic dysfunction-associated steatotic liver disease. Restoration of these rhythms through chronotherapeutic approaches provides an effective method to restore alignment and improve clinical outcomes.
Publish Date 2026-06-16 08:10
Citation

Savvidis C, Ilias I. Letter to the Editor: Circadian and microbial misalignment in metabolic dysfunction-associated steatotic liver disease - mechanistic insights and chronotherapeutic potential. World J Exp Med 2026; 16(2): 118228

URL https://www.wjgnet.com/2220-315x/full/v16/i2/118228.htm
DOI https://doi.org/10.5493/wjem.v16.i2.118228
Full Article (PDF) WJEM-16-118228-with-cover.pdf
Manuscript File 118228_Auto_Edited_060852.docx
Answering Reviewers 118228-answering-reviewers.pdf
Audio Core Tip 118228-audio.mp3
Conflict-of-Interest Disclosure Form 118228-conflict-of-interest-statement.pdf
Copyright License Agreement 118228-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 118228-non-native-speakers.pdf
Peer-review Report 118228-peer-reviews.pdf
Scientific Misconduct Check 118228-scientific-misconduct-check.png
Scientific Editor Work List 118228-scientific-editor-work-list.pdf
CrossCheck Report 118228-crosscheck-report.pdf