| Category |
Pediatrics |
| Manuscript Type |
Observational Study |
| Article Title |
Persistent long-term subclinical myocardial changes in multisystem inflammatory syndrome in children revealed by cardiac magnetic resonance and galectin-3
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Sathish K OV, Rakesh K Pilania, Radhika Semwal, Gopika Sri, Taranpreet Kaur, Pavithra Subramanian, Ankur Jindal, Sanjeev Naganur, Surjit Singh and Manphool Singhal |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Indian Council of Medical Research, Department of Health Research, Ministry of Health and Family Welfare, Government of India, New Delhi |
No. 3/2/MD thesis-June-2022/IH&HRD/2022 |
|
| Corresponding Author |
Rakesh K Pilania, Associate Professor, Pediatric Allergy Immunology Unit, Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research, APC 4A, 4127, Advanced Pediatrics, Pgimer, Chandigarh 160012, Chandīgarh, India. kumarpilania007@gmail.com |
| Key Words |
Multisystem inflammatory syndrome in children; Echocardiography; Cardiac magnetic resonance imaging; Serum galectin; Myocardium |
| Core Tip |
Children recovering from multisystem inflammatory syndrome in children may appear to have complete cardiac recovery on routine echocardiography, yet subtle myocardial abnormalities can persist undetected. Cardiac magnetic resonance imaging performed nearly two years post-illness revealed reduced ejection fraction and elevated native T1 values in a subset of patients, suggesting subclinical myocardial dysfunction. Although serum galectin-3 levels were mildly elevated, they did not correlate with imaging markers. These findings highlight the importance of incorporating cardiac magnetic resonance imaging into long-term follow-up to identify silent myocardial changes and guide future surveillance strategies in multisystem inflammatory syndrome in children survivors. |
| Publish Date |
2026-08-03 01:23 |
| Citation |
OV SK, Pilania RK, Semwal R, Sri G, Kaur T, Subramanian P, Jindal A, Naganur S, Singh S, Singhal M. Persistent long-term subclinical myocardial changes in multisystem inflammatory syndrome in children revealed by cardiac magnetic resonance and galectin-3. World J Clin Pediatr 2026; 15(3): 118237
|
| URL |
https://www.wjgnet.com/2219-2808/full/v15/i3/118237.htm |
| DOI |
https://doi.org/10.5409/wjcp.118237 |
