Publication Name	World Journal of Gastroenterology
Manuscript ID	11826
Country	Italy

Received	2014-06-09 20:49
Peer-Review Started	2014-06-10 20:20
To Make the First Decision	2014-07-09 12:13
Return for Revision	2014-07-14 08:38
Revised	2014-08-10 21:02
Second Decision	2014-09-30 10:03
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-09-30 10:28
Articles in Press	2014-09-30 10:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-12-17 13:48
Publish the Manuscript Online	2015-01-06 09:08

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Dismicrobism in inflammatory bowel disease and colorectal cancer: Changes in response of colocytes
Manuscript Source	Unsolicited Manuscript
All Author List	Giovanni Tomasello, Pietro Tralongo, Provvidenza Damiani, Emanuele Sinagra, Benedetto Di Trapani, Marie Noelle Zeenny, Inaya Hajj Hussein, Abdo Jurjus and Angelo Leone
Funding Agency and Grant Number	Funding Agency Grant Number MIUR EX 60%
Corresponding Author	Angelo Leone, DDS PGCAPHE, Department of Experimental Biomedicine and Clinical Neurosciences, Section of Histology, University of Palermo, Via del vespro 129, 90127 Palermo, Italy. angelo.leone@unipa.it
Key Words	Dismicrobism; Inflammatory bowel disease; Colorectal Cancer; Dysbiosis; Eubiosis; Heat shock proteins
Core Tip	Dysbiosis could be the common denominator of inflammatory bowel disease (IBD) and colorectal cancer. A well balanced gut microbiota promotes the health of colocytes through the production of important compounds and the correct modulation of immune system. Qualitative and quantitative modifications in the bacterial composition are responsible of changes in the biochemistry and in the cell cycle of colocytes. The aim of this work is to focus on the molecular mechanisms that connect dysbiosis, IBD and colorectal cancer. Experimental studies are oriented towards the discovery of new probiotic-based therapies for the treatment and prevention of inflammatory and carcinogenetic processes.
Publish Date	2015-01-06 09:08
Citation	Tomasello G, Tralongo P, Damiani P, Sinagra E, Di Trapani B, Zeenny MN, Hajj Hussein I, Jurjus A, Leone A. Dismicrobism in inflammatory bowel disease and colorectal cancer: Changes in response of colocytes. World J Gastroenterol 2014; 20(48): 18121-18130
URL	http://www.wjgnet.com/1007-9327/full/v20/i48/18121.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i48.18121

Full Article (PDF)	WJG-20-18121.pdf
Full Article (Word)	WJG-20-18121.doc
Manuscript File	11826-Review.docx
Answering Reviewers	11826-Answering reviewers.pdf
Copyright License Agreement	11826-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	11826-Language certificate.pdf
Peer-review Report	11826-Peer review.pdf
Scientific Misconduct Check	11826-CorssCheck.jpg
Scientific Editor Work List	11826-Scientific editor work list.pdf