| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Ophthalmology |
| Manuscript Type |
Review |
| Article Title |
Areas of uncertainty in endophthalmitis care
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Ramesh Venkatesh, Prathibha Hande, Edwin James, Nagesha Krishnappa Chokkahalli, Prashanth Ranganath, Rupal Kathare, Vishma Prabhu, Chaitra Jayadev, Karishma Tendulkar, Pragati Raj, Gaurav Malwe, Shubhangi Tripathi, Preksha Biradar, Alisha Sirsikar and Naresh Kumar Yadav |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ramesh Venkatesh, Consultant, Department of Ophthalmology, Narayana Nethralaya, 121/C. 1st R block, West of Chord Road, Rajaji Nagar, Bangalore 560010, India. vramesh80@yahoo.com |
| Key Words |
Endophthalmitis; Diagnostic uncertainty; Intravitreal therapy; Vitrectomy timing; Antimicrobial resistance |
| Core Tip |
Endophthalmitis remains a vision-threatening ophthalmic emergency in which clinicians must make urgent decisions despite substantial diagnostic and therapeutic uncertainty. Overlapping clinical presentations, frequent culture negativity, evolving antimicrobial resistance, and variable response to treatment complicate early management. Key controversies persist regarding the timing and extent of vitrectomy, selection and dosing of intravitreal antimicrobials, and the role of adjunctive corticosteroids. This review highlights these real-world gray zones and emphasizes the need for individualized, adaptive decision-making rather than rigid, algorithm-based approaches. |
| Publish Date |
2026-02-13 03:14 |
| Citation |
Venkatesh R, Hande P, James E, Chokkahalli NK, Ranganath P, Kathare R, Prabhu V, Jayadev C, Tendulkar K, Raj P, Malwe G, Tripathi S, Biradar P, Sirsikar A, Yadav NK. Areas of uncertainty in endophthalmitis care. World J Clin Cases 2026; 14(6): 118263 |
| URL |
https://www.wjgnet.com/2307-8960/full/v14/i6/118263.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v14.i6.118263 |
