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Articles Published Processes
5/6/2026 8:34:24 AM | Browse: 3 | Download: 16
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Received |
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2025-12-30 07:35 |
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Peer-Review Started |
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2025-12-30 07:35 |
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First Decision by Editorial Office Director |
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2026-01-12 09:40 |
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Return for Revision |
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2026-01-12 09:40 |
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Revised |
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2026-01-22 03:14 |
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Publication Fee Transferred |
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2026-01-23 02:58 |
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Second Decision by Editor |
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2026-02-26 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-26 05:42 |
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Articles in Press |
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2026-02-26 05:42 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-04-22 09:21 |
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Publish the Manuscript Online |
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2026-05-06 08:34 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Microbiology |
| Manuscript Type |
Observational Study |
| Article Title |
Longitudinal changes in the gut microbiota of Vietnamese patients with colorectal cancer undergoing surgery and chemotherapy
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hang Thi Thu Le, Hung Xuan Le, Dao Thi Huyen, Tuan-Anh Tran, Dong Van Quyen, Le Huu Song, Thuan Van Tran, Olivier Thas, Pham Thi Tuyet Nhung and Tam Thi Thanh Tran |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Vietnam National Foundation for Science and Technology Development |
108.04-2021.22 |
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| Corresponding Author |
Tam Thi Thanh Tran, PhD, Department of Life Sciences, University of Science and Technology of Hanoi, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Nghia Do Ward, Hanoi 10000, Viet Nam. tran-thi-thanh.tam@usth.edu.vn |
| Key Words |
Colorectal cancer; Chemotherapy; Longitudinal study; Microbiota profiling; Temporal dynamics; 5-fluorouracil; Oxaliplatin |
| Core Tip |
Gut microbiota plays key roles in intestinal inflammation and tumor development, but also in shaping the anti-tumor immune responses. We longitudinally monitored the gut microbiota of patients with colorectal cancer (CRC) at diagnosis, after surgery and after chemotherapy. Alpha diversity declined and the overall microbial composition (unweighted UniFrac distance) changed at the three timepoints. Overall, CRC-associated pathogens and short-chain fatty acid-producing bacteria were decreased at post-treatment timepoints. Collectively, these results underscore the clinical potential of microbiota-targeted approaches to strengthen the gut barrier and enhance chemotherapy efficacy. |
| Publish Date |
2026-05-06 08:34 |
| Citation |
Le HTT, Le HX, Huyen DT, Tran TA, Quyen DV, Song LH, Tran TV, Thas O, Nhung PTT, Tran TTT. Longitudinal changes in the gut microbiota of Vietnamese patients with colorectal cancer undergoing surgery and chemotherapy. World J Gastroenterol 2026; 32(18): 118267 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i18/118267.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i18.118267 |
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