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6/15/2026 8:38:30 AM | Browse: 1 | Download: 0
Publication Name World Journal of Nephrology
Manuscript ID 118270
Country Pakistan
Received
2025-12-28 14:28
Peer-Review Started
2025-12-28 14:28
First Decision by Editorial Office Director
2026-01-14 08:22
Return for Revision
2026-01-14 08:22
Revised
2026-01-27 15:58
Publication Fee Transferred
Second Decision by Editor
2026-03-05 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-05 07:52
Articles in Press
2026-03-05 07:52
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-06-02 02:16
Publish the Manuscript Online
2026-06-15 08:38
ISSN 2220-6124 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Review
Article Title Post-transplant metabolic dysregulation: Insights and implications for kidney graft survival
Manuscript Source Invited Manuscript
All Author List Tabassum Elahi, Saima Ahmed and Muhammed Mubarak
ORCID
Author(s) ORCID Number
Tabassum Elahi http://orcid.org/0009-0006-9394-022X
Saima Ahmed http://orcid.org/0009-0003-6609-7853
Muhammed Mubarak http://orcid.org/0009-0001-6120-5884
Funding Agency and Grant Number
Corresponding Author Tabassum Elahi, Professor, Department of Nephrology, Sindh Institute of Urology and Transplantation, Chand Bibi Road, Karachi 74200, Sindh, Pakistan. elahitabassum@gmail.com
Key Words Dyslipidemia; Graft survival; Hyperuricemia; Immunosuppressive therapy; Kidney transplantation; Obesity; persistent hyperparathyroidism; Post-transplant diabetes mellitus
Core Tip Kidney transplantation is the preferred treatment for patients progressing to end-stage kidney disease. Several metabolic processes are altered following kidney transplantation, primarily due to the overlap between preexisting risk factors and the side effects of immunosuppressive agents. Among the metabolic alterations, post-transplant diabetes, dyslipidemia, hyperuricemia, secondary hyperparathyroidism, and obesity are the most significant, given their clinical impact and their potential to threaten graft survival and patient outcomes. Lifestyle modification, pharmacological interventions such as sodium-glucose cotransporter-2 inhibitors and glucagon-like peptide-1 receptor agonists, bariatric options, and close monitoring of weight gain are essential strategies, though evidence gaps remain, particularly in the management of hyperparathyroidism.
Publish Date 2026-06-15 08:38
Citation

Elahi T, Ahmed S, Mubarak M. Post-transplant metabolic dysregulation: Insights and implications for kidney graft survival. World J Nephrol 2026; 15(2): 118270

URL https://www.wjgnet.com/2220-6124/full/v15/i2/118270.htm
DOI https://doi.org/10.5527/wjn.v15.i2.118270
Full Article (PDF) WJN-15-118270-with-cover.pdf
Manuscript File 118270_Auto_Edited-YJP.docx
Answering Reviewers 118270-answering-reviewers.pdf
Audio Core Tip 118270-audio.opus
Conflict-of-Interest Disclosure Form 118270-conflict-of-interest-statement.pdf
Copyright License Agreement 118270-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 118270-non-native-speakers.pdf
Peer-review Report 118270-peer-reviews.pdf
Scientific Misconduct Check 118270-scientific-misconduct-check.png
Scientific Editor Work List 118270-scientific-editor-work-list.pdf
CrossCheck Report 118270-crosscheck-report.pdf