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Articles Published Processes
12/2/2015 12:17:00 PM | Browse: 1214 | Download: 1383
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Received |
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2014-06-07 14:49 |
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Peer-Review Started |
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2014-06-08 18:40 |
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To Make the First Decision |
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2014-06-18 18:36 |
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Return for Revision |
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2014-06-19 11:40 |
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Revised |
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2014-06-24 19:41 |
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Second Decision |
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2014-09-10 13:43 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-09-10 14:05 |
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Articles in Press |
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2014-09-10 14:06 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-11-20 09:09 |
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Publish the Manuscript Online |
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2014-12-02 12:25 |
Category |
Medicine, Research & Experimental |
Manuscript Type |
Meta-Analysis |
Article Title |
Systematic review and meta-analysis of Statins-Fibrates therapy in diabetic dyslipidemia patients
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Manuscript Source |
Invited Manuscript |
All Author List |
Shuang Zheng, Yang-Xue Li, Ting-Ting Han, Yao Zhang, Dong-Dong Jiang and Yao-Min Hu |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Scientific Foundation of China |
81270946 |
National Scientific Foundation of China |
81170758 |
National Scientific Foundation of China |
30670988 |
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Corresponding Author |
Yao-Min Hu, PhD, Department of Endocrinology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, NO.160 Pujian Road, Shanghai 200127,
China. amin1031@hotmail.com
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Key Words |
Statin; Fibrate; Dyslipidemia; Type 2 diabetes; Combination therapy |
Core Tip |
Both dyslipidemia and type 2 diabetes were established risk factors of cardiovascular diseases. Statins therapy was highly effective at lowering low density lipoprotein cholesterol (LDL-C). However, despite the increasing use of statins as monotherapy for LDL-C reduction, a significant residual cardiovascular risk was still presented in patients with diabetic dyslipidemia. At the same time, Fenofibrate failed to alter the primary clinical endpoints significantly. How about the efficacy of statins-fibrates combination therapy in patients with diabetic dyslipidemia? The results of this meta-analysis showed the combination therapy was more effective on lipid modification and well tolerated but there was no significant effect on preventing cardiovascular diseases.
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Publish Date |
2014-12-02 12:25 |
Citation |
Zheng S, Li YX, Han TT, Zhang Y, Jiang DD, Hu YM. Systematic review and meta-analysis of Statins-Fibrates therapy in diabetic dyslipidemia patients. World J Meta-Anal 2014; 2(4): 194-203 |
URL |
http://www.wjgnet.com/2308-3840/full/v2/i4/194.htm |
DOI |
http://dx.doi.org/10.13105/wjma.v2.i4.194 |
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