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Articles Published Processes
8/3/2026 1:23:57 AM | Browse: 2 | Download: 0
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Received |
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2025-12-29 03:16 |
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Peer-Review Started |
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2025-12-29 03:21 |
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First Decision by Editorial Office Director |
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2026-01-14 08:15 |
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Return for Revision |
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2026-01-14 08:15 |
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Revised |
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2026-01-27 16:23 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-03-17 03:05 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-17 06:28 |
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Articles in Press |
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2026-03-17 06:28 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-07-17 00:17 |
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Publish the Manuscript Online |
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2026-08-03 01:23 |
| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, General & Internal |
| Manuscript Type |
Randomized Controlled Trial |
| Article Title |
Bovine colostrum for prevention of recurrent urinary tract infections in susceptible children: A randomized controlled trial
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ragia M Said, Abanoub A Wissa, Sara T Wahib and Noha U Hashem |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ragia M Said, Professor, Divsion of Pediatric Nephrology, Department of Pediatrics, Faculty of Medicine, Ain Shams University., Abbaseyah, Cairo 1181, Egypt. ragia_marei@med.asu.edu.eg |
| Key Words |
Recurrent urinary tract infections; respiratory tract infections; gastrointestinal infections; Children; Bovine colostrum |
| Core Tip |
Recurrent urinary tract infections (UTIs) promote the progression of kidney damage in children with congenital anomalies of the kidney and urinary tract, potentially leading to chronic kidney disease. The rising burden of antimicrobial resistance highlights the need for effective nonantibiotic preventive strategies. This randomized, double-blinded, placebo-controlled trial explores oral bovine colostrum (BC), a bioactive prebiotic with immunomodulatory properties, as an adjuvant therapy in these children. Although overall UTIs reduction was not statistically significant, BC significantly reduced cystitis, and showed delayed, month-specific reductions in UTIs, alongside fewer respiratory and gastrointestinal infections. These findings suggest a potential cumulative immunomodulatory benefit of BC in vulnerable pediatric populations. |
| Publish Date |
2026-08-03 01:23 |
| Citation |
Said RM, Wissa AA, Wahib ST, Hashem NU. Bovine colostrum for prevention of recurrent urinary tract infections in susceptible children: A randomized controlled trial. World J Clin Pediatr 2026; 15(3): 118300
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| URL |
https://www.wjgnet.com/2219-2808/full/v15/i3/118300.htm |
| DOI |
https://doi.org/10.5409/wjcp.118300 |
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