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7/23/2026 6:25:01 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 118301
Country China
Received
2026-01-06 07:18
Peer-Review Started
2026-01-06 07:20
First Decision by Editorial Office Director
2026-01-30 09:09
Return for Revision
2026-01-30 09:09
Revised
2026-02-12 16:34
Publication Fee Transferred
Second Decision by Editor
2026-04-13 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-04-13 07:52
Articles in Press
2026-04-13 07:52
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-20 06:35
Publish the Manuscript Online
2026-07-23 06:25
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, General & Internal
Manuscript Type Retrospective Cohort Study
Article Title Risk-stratified assessment of 180-day mortality in severe alcoholic hepatitis
Manuscript Source Unsolicited Manuscript
All Author List Yi-Wen Xv, Jun Ling, Xiao-Gang Hao, Tian-Jiao Xu, Hua Tian, Sa Lv, Shao-Li You and Bing Zhu
ORCID
Author(s) ORCID Number
Tian-Jiao Xu http://orcid.org/0000-0003-3172-1460
Hua Tian http://orcid.org/0009-0005-6034-9348
Sa Lv http://orcid.org/0000-0003-0156-0766
Shao-Li You http://orcid.org/0000-0001-8689-8509
Bing Zhu http://orcid.org/0000-0003-0190-6384
Funding Agency and Grant Number
Funding Agency Grant Number
Capital’s Funds for Health Improvement and Research, China 2024-1-2181
National Science and Technology Major Projects of China 2025ZD01906302
Corresponding Author Bing Zhu, Senior Department of Hepatology, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Middle Road, Fengtai District, Beijing, Beijing 100039, China. zhubing302@163.com
Key Words Maddrey discriminant function; Model for end-stage liver disease; Machine learning; Prognosis; Predictive model
Core Tip This study identified distinct clinical phenotypes of severe alcoholic hepatitis (SAH) using interpretable machine learning, enhancing prognosis precision. By analyzing 1536 patients, we found that creatinine and total bilirubin levels are key predictors of 180-day mortality. A novel two-step risk stratification model revealed significant mortality variations, classifying patients into four tiers with survival rates ranging from 5% to over 50%. This tool facilitates rapid risk assessment and informed treatment decisions, marking a significant advancement in managing SAH.
Publish Date 2026-07-23 06:25
Citation

Xv YW, Ling J, Hao XG, Xu TJ, Tian H, Lv S, You SL, Zhu B. Risk-stratified assessment of 180-day mortality in severe alcoholic hepatitis. World J Gastroenterol 2026; 32(30): 118301

URL https://www.wjgnet.com/1007-9327/full/v32/i30/118301.htm
DOI https://doi.org/10.3748/wjg.118301
Full Article (PDF) WJG-32-118301-with-cover.pdf
STROBE Statement 118301-STROBE-statement.pdf
Manuscript File 118301_Auto_Edited_073617.docx
Answering Reviewers 118301-answering-reviewers.pdf
Audio Core Tip 118301-audio.mp3
Biostatistics Review Certificate 118301-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 118301-conflict-of-interest-statement.pdf
Copyright License Agreement 118301-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 118301-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 118301-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 118301-non-native-speakers.pdf
Supplementary Material 118301-supplementary-material.pdf
Peer-review Report 118301-peer-reviews.pdf
Scientific Misconduct Check 118301-scientific-misconduct-check.png
Scientific Editor Work List 118301-scientific-editor-work-list.pdf
CrossCheck Report 118301-crosscheck-report.pdf