| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Early recurrence risk stratification of hepatocellular carcinoma receiving preoperative radiotherapy: Incorporating clinical and imaging features across treatment phases
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Rong Cong, Bo Chen, Sai-Nan Cheng, Yi-Rui Zhai, Fan Wu, Bing Feng, Le-Yao Wang, Zhao-Wei Chen, Yong-Jian Zhu, Xiao-Hong Ma and Xin-Ming Zhao |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Beijing Hope Run Special Fund of Cancer Foundation of China |
LC2022A14 |
| National High Level Hospital Clinical Research Funding |
80102022505 |
|
| Corresponding Author |
Xin-Ming Zhao, Professor, Department of Diagnostic Radiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17 Panjiayuan Nanli, Chaoyang District, Beijing 100021, China. zhaoxinming@cicams.ac.cn |
| Key Words |
Hepatocellular carcinoma; Preoperative radiotherapy; Hepatectomy; Early recurrence; Magnetic resonance imaging |
| Core Tip |
This study developed two models (baseline-preoperative and postoperative combined models) that integrated multimodal factors across multiple treatment stages in patients with hepatocellular carcinoma who received radiotherapy-based therapy combined with subsequent surgery. These models exhibited comparable and satisfactory performance in predicting early recurrence and allowed risk stratification of early recurrence-free survival, overall recurrence-free survival, and overall survival. Including readily accessible variables, the findings have potential clinical relevance, particularly for preoperative decision-making regarding the timing and personalized planning of surgery after radiotherapy, as well as postoperative management involving adjuvant therapy and close surveillance for high-risk patients. |
| Publish Date |
2026-06-08 09:12 |
| Citation |
Cong R, Chen B, Cheng SN, Zhai YR, Wu F, Feng B, Wang LY, Chen ZW, Zhu YJ, Ma XH, Zhao XM. Early recurrence risk stratification of hepatocellular carcinoma receiving preoperative radiotherapy: Incorporating clinical and imaging features across treatment phases. World J Gastroenterol 2026; 32(23): 118308
|
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i23/118308.htm |
| DOI |
https://doi.org/10.3748/wjg.v32.i23.118308 |
