| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Ophthalmology |
| Manuscript Type |
Observational Study |
| Article Title |
Microbiological spectrum and probability of transmission of infection from ocular tissues of enucleated eyes harvested from septicemic donors
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Aditi Dubey, Priyanka, Deepak Soni, Deepti Chaurasia, Brindha Periasamy, Nikhila C Jain, Deepayan Sarkar, Mamta Singh, Srishti Khullar, Kavita Kumar, Pragyil Chaturvedi and Bhavana Sharma |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Bhavana Sharma, Head, Professor, Department of Ophthalmology, All India Institute of Medical Sciences Bhopal, Saket Nagar, Bhopal 462020, Madhya Pradesh, India. drbhavana_s@yahoo.co.in |
| Key Words |
Corneal transplantation; Septicemia; Corneal blindness; Donor tissue contamination; Eye banking |
| Core Tip |
Corneal transplantation remains an important sight restoring procedure, but has major demand-supply gap of donor corneas, worsened by exclusion of septicemic donors due to presumed infection risk. This bicentric cross-sectional study evaluated the microbiological spectrum of ocular tissues harvested from septicemic donors and their potential risk of infection transmission. Cultures from conjunctiva, cornea, sclera, aqueous, vitreous, and post-mortem blood were assessed and correlated. Microbial growth rates were comparable between groups, with organisms largely reflecting commensal flora. Only one corneal and scleral sample matched blood culture isolates. A strong association was found between longer death-to-retrieval time and contamination. Overall, septicemia did not significantly compromise tissue sterility, suggesting potential reconsideration of transplantation guidelines to reduce tissue wastage. |
| Publish Date |
2026-05-29 08:41 |
| Citation |
Dubey A, P, Soni D, Chaurasia D, Periasamy B, Jain NC, Sarkar D, Singh M, Khullar S, Kumar K, Chaturvedi P, Sharma B. Microbiological spectrum and probability of transmission of infection from ocular tissues of enucleated eyes harvested from septicemic donors. World J Transplant 2026; 16(2): 118357 |
| URL |
https://www.wjgnet.com/2220-3230/full/v16/i2/118357.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v16.i2.118357 |
