Publication Name	World Journal of Gastroenterology
Manuscript ID	11837
Country	China

Received	2014-06-07 14:13
Peer-Review Started	2014-06-07 17:33
To Make the First Decision	2014-06-27 17:48
Return for Revision	2014-07-02 17:19
Revised	2014-07-12 16:56
Second Decision	2014-08-28 10:02
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-08-28 10:37
Articles in Press	2014-08-28 10:59
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-09-16 03:38
Typeset the Manuscript	2014-12-18 16:33
Publish the Manuscript Online	2015-01-06 09:08

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Autobiography
Article Title	Twist1 correlates with poor differentiation and progression in gastric adenocarcinoma via elevation of FGFR2 expression
Manuscript Source	Unsolicited Manuscript
All Author List	Dong-Yuan Zhu, Qi-Sen Guo, Yan-Liang Li, Bin Cui, Jun Guo, Ji-Xiao Liu and Peng Li
Funding Agency and Grant Number	Funding Agency Grant Number Medicine and Sanitation Development Project of Shandong Province 2014WS0323
Corresponding Author	Peng Li, MD, Department of Medical Oncology, Yantai Yuhuangding Hospital affiliated to Qingdao University, 20 Yudong Road, Yantai 264000, Shandong Province, China. lipengyuhuangding@163.com
Key Words	Twist-related protein 1; Fibroblast growth factor receptor 2; Gastric adenocarcinoma; Cancer differentiation; Cancer progression
Core Tip	The underlying mechanism of Twist1 and fibroblast growth factor receptor (FGFR)2 function in gastric cancer has not been fully elucidated. We assessed expression of Twist1 and FGFR2 in gastric adenocarcinoma tissues by immunohistochemistry and polymerase chain reaction, and demonstrated that Twist1 and FGFR2 expression was significantly associated with differentiation of gastric adeno?carcinoma tissue. We found that Twist1 can function as a transcription factor to promote FGFR2 expression. Moreover, Twist1 can induce proliferation, invasion and epithelial-mesenchymal transition (EMT) of gastric cells, in which FGFR2 is required in the Twist1-induced cell invasion and EMT.
Publish Date	2015-01-06 09:08
Citation	Zhu DY, Guo QS, Li YL, Cui B, Guo J, Liu JX, Li P. Twist1 correlates with poor differentiation and progression in gastric adenocarcinoma via elevation of FGFR2 expression. World J Gastroenterol 2014; 20(48): 18306-18315
URL	http://www.wjgnet.com/1007-9327/full/v20/i48/18306.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i48.18306

Full Article (PDF)	WJG-20-18306.pdf
Full Article (Word)	WJG-20-18306.doc
Manuscript File	11837-Review.doc
Answering Reviewers	11837-Answering reviewers.pdf
Copyright License Agreement	11837-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	11837-Language certificate.PDF
Peer-review Report	11837-Peer review.pdf
Scientific Misconduct Check	11837-CorssCheck.jpg
Scientific Editor Work List	11837-Scientific editor work list.pdf