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Publication Name World Journal of Methodology
Manuscript ID 118399
Country India
Received
2025-12-31 01:22
Peer-Review Started
2025-12-31 01:22
First Decision by Editorial Office Director
2026-01-23 09:17
Return for Revision
2026-01-23 09:17
Revised
2026-01-26 12:55
Publication Fee Transferred
Second Decision by Editor
2026-02-25 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-25 07:16
Articles in Press
2026-02-25 07:16
Edit the Manuscript by Language Editor
2026-03-06 20:10
Typeset the Manuscript
2026-06-18 08:55
Publish the Manuscript Online
2026-07-10 10:11
ISSN 2222-0682 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Management of constipation: A narrative review of evolving strategies and methodological challenges
Manuscript Source Invited Manuscript
All Author List Manjeet Kumar Goyal, Gayatri Brahmandam, Rishi Chowdhary, Sowmya Durga Subhasri Guna, Dhruvi Shah, Prerna Goyal, Ashita Rukmini Vuthaluru and Omesh Goyal
ORCID
Author(s) ORCID Number
Manjeet Kumar Goyal http://orcid.org/0000-0002-5511-2099
Rishi Chowdhary http://orcid.org/0000-0002-3075-0684
Omesh Goyal http://orcid.org/0000-0002-6347-0988
Funding Agency and Grant Number
Corresponding Author Omesh Goyal, Department of Gastroenterology, Dayanand Medical College and Hospital, Tagore Nagar, Ludhiana 141001, Punjab, India. dromeshgoyal@gmail.com
Key Words Constipation; Gastrointestinal motility disorders; Irritable bowel syndrome; Defecation disorders; Colonic transit; Pelvic floor disorders; Prokinetic agents; Disorders of gut-brain interactions
Core Tip Chronic constipation is a heterogeneous disorder encompassing distinct pathophysiologic phenotypes, including normal-transit constipation, slow-transit constipation, and defecatory disorders, as well as a broad range of secondary organic causes. Failure to recognize these subtypes contributes to suboptimal treatment responses and inconsistent outcomes in both clinical practice and trials. Accurate diagnosis requires a structured, stepwise approach integrating careful history, targeted physical examination, and selective use of physiologic and imaging investigations. Management should be phenotype-driven, combining lifestyle measures, pharmacologic therapy, and pelvic floor–directed interventions when appropriate. Emphasizing mechanism-based evaluation and individualized treatment strategies is essential to improve long-term outcomes and reduce unnecessary therapeutic escalatio
Publish Date 2026-07-10 10:11
Citation

Goyal MK, Brahmandam G, Chowdhary R, Subhasri Guna SD, Shah D, Goyal P, Vuthaluru AR, Goyal O. Management of constipation: A narrative review of evolving strategies and methodological challenges. World J Methodol 2026; 16(3): 118399

URL https://www.wjgnet.com/2222-0682/full/v16/i3/118399.htm
DOI https://doi.org/10.5662/wjm.118399
Full Article (PDF) WJM-16-118399-with-cover.pdf
Manuscript File 118399_Auto_Edited-YJP.docx
Answering Reviewers 118399-answering-reviewers.pdf
Audio Core Tip 118399-audio.mp4
Conflict-of-Interest Disclosure Form 118399-conflict-of-interest-statement.pdf
Copyright License Agreement 118399-copyright-assignment.pdf
Peer-review Report 118399-peer-reviews.pdf
Scientific Misconduct Check 118399-scientific-misconduct-check.png
Scientific Editor Work List 118399-scientific-editor-work-list.pdf
CrossCheck Report 118399-crosscheck-report.pdf