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8/3/2026 1:23:55 AM | Browse: 2 | Download: 1
Publication Name World Journal of Clinical Pediatrics
Manuscript ID 118413
Country India
Received
2026-01-15 03:41
Peer-Review Started
2026-01-15 03:45
First Decision by Editorial Office Director
2026-02-03 09:44
Return for Revision
2026-02-03 09:44
Revised
2026-02-21 18:12
Publication Fee Transferred
Second Decision by Editor
2026-04-08 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-04-08 07:33
Articles in Press
2026-04-08 07:33
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-23 03:49
Publish the Manuscript Online
2026-08-03 01:23
ISSN 2219-2808 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pediatrics
Manuscript Type Prospective Study
Article Title Transforming central line associated blood stream infection prevention in neonates: Results from a multimodal quality improvement initiative
Manuscript Source Invited Manuscript
All Author List Anish Pillai, Nandkishor Kabra, Anuja Nayak, Mayuri Bhanushali, Haribalakrishna Balasubramanian and Sandesh Shivananda
ORCID
Author(s) ORCID Number
Anish Pillai http://orcid.org/0000-0002-8353-5048
Nandkishor Kabra http://orcid.org/0000-0002-9277-9108
Anuja Nayak http://orcid.org/0000-0002-1672-8624
Mayuri Bhanushali http://orcid.org/0009-0003-3435-8078
Haribalakrishna Balasubramanian http://orcid.org/0000-0002-1305-1005
Sandesh Shivananda http://orcid.org/0000-0001-5323-1900
Funding Agency and Grant Number
Corresponding Author Nandkishor Kabra, Head, Professor, Department of Neonatology, Surya Hospitals, Mangal Ashirvad, S.V Road, Santacruz West, Mumbai 400054, Mahārāshtra, India. drkabra@suryahospitals.com
Key Words Quality improvement; Plan-Do-Study-Act cycle; Neonatal sepsis; Prevention bundle; Infection control; Central line-associated bloodstream infections
Core Tip A structured, multimodal quality improvement initiative led to a substantial and sustained reduction in neonatal central line associated blood stream infection rates in a level-3 neonatal intensive care unit. By strengthening hand hygiene, customizing central line care bundles, reinforcing environmental cleaning, conducting regular audits, and providing ongoing nursing education through iterative Plan-Do-Study-Act cycles, central line associated blood stream infection rates fell by over 80% and remained low for 18 months. This low-cost, pragmatic approach is feasible and reproducible in resource-constrained neonatal intensive care unit settings, including low- and middle-income countries.
Publish Date 2026-08-03 01:23
Citation

Pillai A, Kabra N, Nayak A, Bhanushali M, Balasubramanian H, Shivananda S. Transforming central line associated blood stream infection prevention in neonates: Results from a multimodal quality improvement initiative. World J Clin Pediatr 2026; 15(3): 118413

URL https://www.wjgnet.com/2219-2808/full/v15/i3/118413.htm
DOI https://doi.org/10.5409/wjcp.118413
Full Article (PDF) WJCP-15-118413-with-cover.pdf
CONSORT 2010 Statement 118413-CONSORT-2010-statement.pdf
Manuscript File 118413_Auto_Edited_005654.docx
Answering Reviewers 118413-answering-reviewers.pdf
Audio Core Tip 118413-audio.mp3
Biostatistics Review Certificate 118413-biostatistics-statement.pdf
Clinical Trial Registration Statement 118413-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 118413-conflict-of-interest-statement.pdf
Copyright License Agreement 118413-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 118413-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 118413-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 118413-non-native-speakers.pdf
Supplementary Material 118413-supplementary-material.pdf
Peer-review Report 118413-peer-reviews.pdf
Scientific Misconduct Check 118413-scientific-misconduct-check.png
Scientific Editor Work List 118413-scientific-editor-work-list.pdf
CrossCheck Report 118413-crosscheck-report.pdf