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5/13/2026 8:18:31 AM | Browse: 5 | Download: 39
Publication Name World Journal of Clinical Pediatrics
Manuscript ID 118421
Country India
Received
2026-01-07 03:33
Peer-Review Started
2026-01-07 03:33
First Decision by Editorial Office Director
2026-01-16 06:53
Return for Revision
2026-01-16 06:53
Revised
2026-01-29 11:43
Publication Fee Transferred
Second Decision by Editor
2026-02-13 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-13 05:48
Articles in Press
2026-02-13 05:48
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-04-24 02:12
Publish the Manuscript Online
2026-05-13 08:18
ISSN 2219-2808 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pediatrics
Manuscript Type Observational Study
Article Title Study on intravenous immunoglobulin use in a pediatric intensive care unit of a tertiary care center
Manuscript Source Invited Manuscript
All Author List Poovazhagi Varadarajan, Seenivasan Subramani, Vasanth Jeyaram, Lakshmi S Velmurugan, Raghul Jayaseelan and Gomathy Srividya Venugopal
ORCID
Author(s) ORCID Number
Poovazhagi Varadarajan http://orcid.org/0000-0002-1623-9652
Seenivasan Subramani http://orcid.org/0000-0002-3269-1702
Vasanth Jeyaram http://orcid.org/0009-0003-5331-5751
Lakshmi S Velmurugan http://orcid.org/0009-0003-6282-7302
Raghul Jayaseelan http://orcid.org/0009-0009-3891-4223
Gomathy Srividya Venugopal http://orcid.org/0000-0002-4082-3453
Funding Agency and Grant Number
Corresponding Author Seenivasan Subramani, Assistant Professor, Consultant, DM, Department of Pediatric Intensive Care, Institute of Child Health and Hospital for Children, Madras Medical College, Tamil Salai, Egmore Chennai, Chennai 600008, Tamil Nādu, India. seeni.sholing@gmail.com
Key Words Intravenous immunoglobulin; Pediatric intensive care unit; Off label use; Strength of recommendation; Level of evidence
Core Tip This study evaluates intravenous immunoglobulin (IVIG) use in a pediatric intensive care unit, highlighting indications, dosing, evidence support, and outcomes. The commonest indication was immunological diseases followed by neurological illness, infections, hematological diseases and cardiac diseases. Strength of recommendation varies in different diseases. Off label use was seen in about one -fifth of patients. Adverse effects were minimal. Evidence is lacking regarding the use of IVIG in many diseases. The study suggests multicentric trials to define proper indications of IVIG.
Publish Date 2026-05-13 08:18
Citation

Varadarajan P, Subramani S, Jeyaram V, Velmurugan LS, Jayaseelan R, Venugopal GS. Study on intravenous immunoglobulin use in a pediatric intensive care unit of a tertiary care center. World J Clin Pediatr 2026; 15(2): 118421

URL https://www.wjgnet.com/2219-2808/full/v15/i2/118421.htm
DOI https://dx.doi.org/10.5409/wjcp.v15.i2.118421
Full Article (PDF) WJCP-15-118421-with-cover.pdf
STROBE Statement 118421-STROBE-statement.pdf
Manuscript File 118421_Auto_Edited_070916.docx
Answering Reviewers 118421-answering-reviewers.pdf
Audio Core Tip 118421-audio.mp3
Biostatistics Review Certificate 118421-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 118421-conflict-of-interest-statement.pdf
Copyright License Agreement 118421-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 118421-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 118421-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 118421-non-native-speakers.pdf
Peer-review Report 118421-peer-reviews.pdf
Scientific Misconduct Check 118421-scientific-misconduct-check.png
Scientific Editor Work List 118421-scientific-editor-work-list.pdf
CrossCheck Report 118421-crosscheck-report.pdf