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4/13/2026 7:23:21 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastrointestinal Endoscopy
Manuscript ID 118422
Country Italy
Received
2026-01-02 15:13
Peer-Review Started
2026-01-02 15:14
First Decision by Editorial Office Director
2026-01-06 09:10
Return for Revision
2026-01-06 09:10
Revised
2026-01-19 20:54
Publication Fee Transferred
Second Decision by Editor
2026-02-26 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-26 09:44
Articles in Press
2026-02-26 09:44
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-04-01 00:42
Publish the Manuscript Online
2026-04-13 07:23
ISSN 1948-5190 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Reference range of pancreatic strain histogram by endoscopic ultrasound elastography: A pilot study
Manuscript Source Invited Manuscript
All Author List Carmen Laurenza, Nunzio Zignani, Biagio Elvo, Luca Pignata, Francesco Frigo, Imma Di Luna, Sara Soro, Dario Dagani, Andrea Drago and Roberto Grassia
ORCID
Author(s) ORCID Number
Carmen Laurenza http://orcid.org/0000-0002-4187-1799
Nunzio Zignani http://orcid.org/0009-0004-2695-3157
Biagio Elvo http://orcid.org/0000-0001-5695-0310
Luca Pignata http://orcid.org/0009-0004-4145-4049
Francesco Frigo http://orcid.org/0000-0002-4503-4293
Sara Soro http://orcid.org/0000-0002-4802-8403
Andrea Drago http://orcid.org/0000-0002-9777-8665
Roberto Grassia http://orcid.org/0000-0003-4491-4050
Funding Agency and Grant Number
Corresponding Author Nunzio Zignani, MD, Department of Pathophysiology and Transplantation, University of Milan, Via Festa Del Perdono 7, Milan 20122, Lombardy, Italy. zignani.nunzio@gmail.com
Key Words Semi-quantitative elastography; Strain histogram elastography; Chronic pancreatitis; Pancreatic stiffness; Elastography; Endoscopic ultrasound
Core Tip This pilot study evaluates endoscopic ultrasound-elastography using strain histogram (SH) analysis to improve the diagnosis of chronic pancreatitis (CP), which remains challenging in its early stages. The study compared 95 healthy controls with 48 CP patients to establish reference stiffness values. Results showed that CP patients had significantly higher pancreatic stiffness, indicated by lower SH values compared to healthy subjects (median 72 vs 116, P < 0.01). In conclusion, SH analysis effectively differentiates healthy tissue from CP, providing a safe tool for identifying preclinical pathological changes.
Publish Date 2026-04-13 07:23
Citation

Laurenza C, Zignani N, Elvo B, Pignata L, Frigo F, Di Luna I, Soro S, Dagani D, Drago A, Grassia R. Reference range of pancreatic strain histogram by endoscopic ultrasound elastography: A pilot study. World J Gastrointest Endosc 2026; 18(4): 118422

URL https://www.wjgnet.com/1948-5190/full/v18/i4/118422.htm
DOI https://dx.doi.org/10.4253/wjge.v18.i4.118422
Full Article (PDF) WJGE-18-118422-with-cover.pdf
STROBE Statement 118422-STROBE-statement.pdf
Manuscript File 118422_Auto_Edited_054646.docx
Answering Reviewers 118422-answering-reviewers.pdf
Audio Core Tip 118422-audio.m4a
Biostatistics Review Certificate 118422-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 118422-conflict-of-interest-statement.pdf
Copyright License Agreement 118422-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 118422-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 118422-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 118422-non-native-speakers.pdf
Peer-review Report 118422-peer-reviews.pdf
Scientific Misconduct Check 118422-scientific-misconduct-check.png
Scientific Editor Work List 118422-scientific-editor-work-list.pdf
CrossCheck Report 118422-crosscheck-report.pdf