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Publication Name World Journal of Biological Chemistry
Manuscript ID 118440
Country Cameroon
Received
2026-01-04 08:48
Peer-Review Started
2026-01-04 08:49
First Decision by Editorial Office Director
2026-01-20 08:22
Return for Revision
2026-01-20 08:22
Revised
2026-02-03 08:20
Publication Fee Transferred
2026-03-08 16:50
Second Decision by Editor
2026-05-21 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-21 10:08
Articles in Press
2026-05-21 10:08
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-28 01:57
Publish the Manuscript Online
2026-06-04 07:37
ISSN 1949-8454 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © Author(s) (or their employer(s)) 2026. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Case Control Study
Article Title Glycemic status, antioxidant enzyme and lipid peroxidation among patients with diabetes mellitus in Buea Regional Hospital in Cameroon
Manuscript Source Unsolicited Manuscript
All Author List Ebot Walter Ojong, Leon Brandon Nyake Mbu Akime, Ayuk Betrand Tambe, Armel Jackson Seukep, Elvis Amih Ofon, Tabe Cletus Akwa and Chugbe Nathaneal Sawah
ORCID
Author(s) ORCID Number
Ebot Walter Ojong http://orcid.org/0000-0002-6059-5734
Ayuk Betrand Tambe http://orcid.org/0000-0002-5023-4273
Chugbe Nathaneal Sawah http://orcid.org/0009-0008-5816-6974
Funding Agency and Grant Number
Corresponding Author Ebot Walter Ojong, Academic Fellow, Lecturer, PhD, Medical Laboratory Science, Faculty of Health Sciences, University of Buea, Molyko Quarter, Buea P.O. Box 63, South-West, Cameroon. ebot.ojong@ubuea.cm
Key Words Type 2 diabetes mellitus; Glycemic control; Lipid peroxidation; Oxidative stress; Antioxidant; Buea
Core Tip Hyperglycemia in type 2 diabetes mellitus (T2DM) generates free radicals which reduce antioxidant enzyme activities leading to oxidative stress. The influence of glycemic control on enhanced free-radical activity is poorly understood and no study has been conducted in Buea Health District. This hospital-based case-control study evaluated levels of malondialdehyde and catalase in patients with T2DM with different glycemic status and compared them with healthy subjects. We found a higher prevalence of lipid peroxidation and a higher proportion of reduced serum antioxidant activity in patients with T2DM with poor glycemic control. Routine assessment of lipid peroxidation markers and antioxidant enzyme activities in patients with T2DM especially those with poor glycemic control is recommended in improving patient care and mitigating complications.
Publish Date 2026-06-04 07:37
Citation

Ojong EW, Nyake Mbu Akime LB, Tambe AB, Seukep AJ, Ofon EA, Akwa TC, Sawah CN. Glycemic status, antioxidant enzyme and lipid peroxidation among patients with diabetes mellitus in Buea Regional Hospital in Cameroon. World J Biol Chem 2026; 17(2): 118440

URL https://www.wjgnet.com/1949-8454/full/v17/i2/118440.htm
DOI https://doi.org/10.4331/wjbc.v17.i2.118440
Full Article (PDF) WJBC-17-118440-with-cover.pdf
STROBE Statement 118440-STROBE-statement.pdf
Manuscript File 118440_Auto_Edited_070114.docx
Answering Reviewers 118440-answering-reviewers.pdf
Audio Core Tip 118440-audio.m4a
Biostatistics Review Certificate 118440-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 118440-conflict-of-interest-statement.pdf
Copyright License Agreement 118440-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 118440-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 118440-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 118440-non-native-speakers.pdf
Peer-review Report 118440-peer-reviews.pdf
Scientific Misconduct Check 118440-scientific-misconduct-check.png
Scientific Editor Work List 118440-scientific-editor-work-list.pdf
CrossCheck Report 118440-crosscheck-report.pdf