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Articles Published Processes
5/29/2026 8:41:35 AM | Browse: 1 | Download: 14
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Received |
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2026-01-06 06:32 |
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Peer-Review Started |
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2026-01-06 06:42 |
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First Decision by Editorial Office Director |
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2026-02-09 09:32 |
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Return for Revision |
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2026-02-09 09:32 |
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Revised |
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2026-02-28 20:47 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-04-01 02:39 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-04-01 08:41 |
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Articles in Press |
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2026-04-01 08:41 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-05-18 03:54 |
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Publish the Manuscript Online |
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2026-05-29 08:41 |
| ISSN |
2220-3230 (online) |
| Open Access |
Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Retrospective Study |
| Article Title |
Immunologic clustering of donor-specific antibodies and clinical outcomes in kidney transplant recipients
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Salem H Al-Qurashi, Muhammad Abdul Mabood Khalil, Hinda Hassan Khideer Mahmood, Maram Majid Alsharif, Yara Faisal Alqurashi, Lama Alghamdi, Rawan A Al-Ghamdi, Zeyad Adel Alsaedi, Aileen Jean Dela Cruz, Ghaleb A Aboasamh and Nihal Mohammed Sadagah |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Muhammad Abdul Mabood Khalil, FRCP, Center of Renal Diseases and Transplantation, King Fahad Armed Forces Hospital, Al Kurnaysh Br Road, Al Andalus, Jeddah 23311, Makkah al Mukarramah, Saudi Arabia. doctorkhalil1975@hotmail.com |
| Key Words |
Immunological clustering; Donor-specific antibodies; Renal allograft outcomes; Machine learning; Human leukocytes antigen |
| Core Tip |
Donor-specific antibodies (DSA) in kidney transplant recipients (KTR) are associated with variable immunologic risk, which is not always well defined by DSA class or mean fluorescence intensity alone. In this study, an unsupervised machine learning approach was used to group DSA-positive recipients based on antibody characteristics and transplant-related factors. These groups showed apparent differences in early post-transplant risk profiles. Patients with broader and stronger antibody responses were more likely to experience adverse early outcomes, whereas those with a limited antibody burden had favorable graft function. This approach may help refine risk assessment and support more individualized management of DSA-positive KTR. |
| Publish Date |
2026-05-29 08:41 |
| Citation |
Al-Qurashi SH, Khalil MAM, Mahmood HHK, Alsharif MM, Alqurashi YF, Alghamdi L, A Al-Ghamdi R, Alsaedi ZA, Cruz AJD, Aboasamh GA, Sadagah NM. Immunologic clustering of donor-specific antibodies and clinical outcomes in kidney transplant recipients. World J Transplant 2026; 16(2): 118450 |
| URL |
https://www.wjgnet.com/2220-3230/full/v16/i2/118450.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v16.i2.118450 |
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