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Articles Published Processes
6/22/2026 8:40:59 AM | Browse: 0 | Download: 0
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Received |
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2026-01-04 05:46 |
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Peer-Review Started |
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2026-01-04 05:48 |
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First Decision by Editorial Office Director |
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2026-01-12 09:14 |
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Return for Revision |
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2026-01-12 09:14 |
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Revised |
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2026-02-19 06:47 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-05-19 02:38 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-05-19 04:19 |
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Articles in Press |
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2026-05-19 04:19 |
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Edit the Manuscript by Language Editor |
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2026-05-26 20:57 |
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Typeset the Manuscript |
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2026-06-10 00:40 |
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Publish the Manuscript Online |
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2026-06-22 08:41 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Minireviews |
| Article Title |
Radiation-induced cardiotoxicity in lung cancer: Current landscape and future directions
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Xiao-Luan Lin, Jia-Rong Li and Ren-Xian Xie |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ren-Xian Xie, Department of Radiation Oncology, Cancer Hospital of Shantou University Medical College, No. 7 Raoping Road, Shantou 515000, Guangdong Province, China. 21rxxie@stu.edu.cn |
| Key Words |
Radiation-induced heart disease; Lung cancer; Cardiotoxicity; Dose-volume parameters; Immunotherapy; Cardio-oncology |
| Core Tip |
This mini-review examines the evolving comprehension of radiation-induced cardiotoxicity in lung cancer, emphasizing the transition from whole-heart to cardiac substructure-focused dose evaluation and risk prediction. The primary focus is on utilizing advanced predictive modeling techniques, such as radiomics and machine learning, to achieve personalized risk stratification. Importantly, the methodological paradigm developed for predicting radiation pneumonitis is highlighted as a crucial surrogate framework for creating analogous models for cardiotoxicity, given the similarities in injury mechanisms and data-driven modeling approaches. Additionally, the review underscores the essential need for integrated cardio-oncology management strategies in the context of combination therapies involving immunotherapy and targeted agents, with the goal of maintaining long-term cardiovascular health without compromising oncologic outcomes. |
| Publish Date |
2026-06-22 08:41 |
| Citation |
Lin XL, Li JR, Xie RX. Radiation-induced cardiotoxicity in lung cancer: Current landscape and future directions. World J Clin Oncol 2026; 17(6): 118494
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| URL |
https://www.wjgnet.com/2218-4333/full/v17/i6/118494.htm |
| DOI |
https://doi.org/10.5306/wjco.118494 |
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