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Articles Published Processes
5/26/2026 3:52:13 AM | Browse: 1 | Download: 1
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Received |
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2026-01-12 01:41 |
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Peer-Review Started |
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2026-01-12 01:42 |
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First Decision by Editorial Office Director |
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2026-01-23 10:06 |
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Return for Revision |
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2026-01-23 12:17 |
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Revised |
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2026-02-06 05:27 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-04-22 02:38 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-04-22 08:04 |
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Articles in Press |
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2026-04-22 08:04 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-05-12 01:16 |
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Publish the Manuscript Online |
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2026-05-26 03:52 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Opinion Review |
| Article Title |
Survival gap in gallbladder cancer: Bridging tumor biology and healthcare system logistics
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Bruno Mirandola Bulisani |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Bruno Mirandola Bulisani, MD, PhD, Department of Digestive Surgery, Centro Universitário FMABC Santo André, Brazil Centro Universitário FMABC, São Caetano do Sul 09551200, São Paulo, Brazil. brunomirandola@hotmail.com |
| Key Words |
Gallbladder carcinoma; Incidental gallbladder cancer; Healthcare logistics; Referral pathways; Radical re-resection; Molecular stratification; Neoadjuvant therapy; Real-world evidence; Therapeutic window; Hepatobiliary surgery |
| Core Tip |
Gallbladder cancer (GBC) prognosis is traditionally viewed through the lens of aggressive tumor biology. However, in intermediate-incidence regions like Brazil, systemic fragmentation often prevents curative intent. This opinion review proposes a paradigm shift: Classifying healthcare logistics as a modifiable prognostic factor. By integrating molecular stratification, focusing on TP53 and HER2, with logistical “auto-alerts” and neoadjuvant “biological filters”, we can bridge the survival gap. Optimizing the “therapeutic window” between incidental diagnosis and radical surgery is as crucial as the surgical technique itself in transforming GBC outcomes. |
| Publish Date |
2026-05-26 03:52 |
| Citation |
Bulisani BM. Survival gap in gallbladder cancer: Bridging tumor biology and healthcare system logistics. World J Hepatol 2026; 18(5): 118508 |
| URL |
https://www.wjgnet.com/1948-5182/full/v18/i5/118508.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v18.i5.118508 |
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