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Articles Published Processes
6/25/2026 8:21:21 AM | Browse: 0 | Download: 0
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Received |
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2026-01-05 08:24 |
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Peer-Review Started |
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2026-01-05 08:28 |
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First Decision by Editorial Office Director |
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2026-01-14 08:33 |
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Return for Revision |
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2026-01-14 08:33 |
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Revised |
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2026-01-20 09:07 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-02-24 02:52 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-24 08:57 |
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Articles in Press |
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2026-02-24 08:57 |
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Edit the Manuscript by Language Editor |
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2026-02-25 18:05 |
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Typeset the Manuscript |
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2026-05-26 09:31 |
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Publish the Manuscript Online |
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2026-06-25 08:21 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell & Tissue Engineering |
| Manuscript Type |
Opinion Review |
| Article Title |
Mesenchymal stem cells mediate the temporal modulation of aging-related changes
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ilya D Klabukov, Anna Smirnova, Yana Sulina and Denis S Baranovskii |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ilya D Klabukov, Associate Professor, Head, PhD, Department of Regenerative Medicine, National Medical Research Radiological Center, 4 Koroleva Street, Obninsk 249036, Kaluzhskaya Oblast’, Russia. ilya.klabukov@gmail.com |
| Key Words |
Adverse events; Aging; Cell therapy; Immunosenescence; Mesenchymal stem cells; Rejuvenation; Senescence-associated secretory phenotype; Senescence |
| Core Tip |
Mesenchymal stem cells show promise in regenerative medicine, but their use in elderly patients requires careful consideration. Aging presents unique challenges, such as immunosenescence, an increased risk of cancer, cellular senescence, and vascular complications. These challenges underscore the necessity of rigorous preclinical and clinical studies to evaluate the safety and efficacy of MSC therapy. This could lead to a reevaluation of the role of some of MSC subpopulations as novel unconventional therapeutic targets. |
| Publish Date |
2026-06-25 08:21 |
| Citation |
Klabukov ID, Smirnova A, Sulina Y, Baranovskii DS. Mesenchymal stem cells mediate the temporal modulation of aging-related changes. World J Stem Cells 2026; 18(6): 118524
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| URL |
https://www.wjgnet.com/1948-0210/full/v18/i6/118524.htm |
| DOI |
https://doi.org/10.4252/wjsc.118524 |
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